Fertility :: Scientists discover fertility genes

Scientists at the Waksman Institute of Microbiology at Rutgers, The State University of New Jersey, have zeroed in on genes which are essential for fertilization . The proteins encoded by these genes are similar to low density lipoprotein (LDL) receptors, known from cholesterol and fat metabolism but never before specifically implicated in fertilization.

HIV :: Combination Microbicides Protect Against HIV-Like Virus

Experiments in female monkeys have for the first time shown that when used in combination, vaginal gels known as microbicides can protect against an HIV-like virus. The research, funded largely by the National Institute of Allergy and Infectious Diseases (NIAID), one of the National Institutes of Health (NIH), suggests that similar combination microbicides could potentially provide a safe, effective and practical way to prevent HIV transmission to women, according to study investigators.

Influenza :: Promise Against H5N1 Influenza Virus

Experiments in mice show that an antiviral drug currently used against annual influenza strains also can suppress the deadly influenza virus that has spread from birds to humans, killing dozens of people in Vietnam, Cambodia and Thailand since early 2004. This study, the first published report conducted on oseltamivir against the H5N1 influenza strain circulating in Vietnam, found that the drug, sold commercially as Tamiflu, dramatically boosted the survival rate of infected mice.

HIV :: HIV Therapy Greatly Extends Life of Key T Cells

Interleukin-2 (IL-2), an immune-boosting drug used experimentally in HIV therapy, greatly increases the lifespan of certain subsets of immune system T cells in some HIV-positive people who respond to this therapy, discovered researchers from the National Institutes of Health (NIH) Clinical Center and the National Institute of Allergy and Infectious Diseases (NIAID), part of the NIH. A report describing the study, led by the Clinical Center?s Joseph A. Kovacs, M.D., appears online today in The Journal of Clinical Investigation.

Allergy :: Food Allergy Research Consortium Focuses on Peanut Allergy

The only advice doctors can give to the 4 percent of Americans with potentially life-threatening food allergies is to avoid the culprit food, often nuts or shellfish. But that may change as researchers in a new Food Allergy Research Consortium, announced, strive to develop therapies to treat and prevent food allergy.