Diabetes :: Scientists show that mitochondrial DNA variants are linked to risk factors for type 2 diabetes

Today, researchers report for the first time that genetic variants in mitochondria?energy-producing structures harboring DNA that are inherited only from the mother?are directly linked to metabolic markers for type 2 diabetes. The study, which highlights the role of mitochondrial genome variation in the pathogenesis of common diseases, is published online in Genome Research (www.genome.org).

Diabetes :: Abnormal fat metabolism underlies heart problems in diabetic patients

Heart disease hits people with diabetes twice as often as people without diabetes. In those with diabetes, cardiovascular complications occur at an earlier age and often result in premature death, making heart disease the major killer of diabetic people. But why is heart disease so prevalent among diabetics.

Diabetes :: Female advantage in kidney disease does not extend to diabetic women

Women have a ?female advantage? when it comes to chronic kidney disease. When compared to men, they have fewer and less severe episodes of this disorder throughout most of their lives. That advantage disappears, however, when the woman is diabetic. For reasons still unclear, diabetic women ? regardless of age ? are diagnosed with kidney and heart diseases almost as frequently as men.

Diabetes :: Bone as therapeutic target for type 2 diabetes

Bones are typically thought of as calcified, inert structures, but researchers at Columbia University Medical Center have now identified a surprising and critically important novel function of the skeleton. They?ve shown for the first time that the skeleton is an endocrine organ that helps control our sugar metabolism and weight and, as such, is a major determinant of the development of type 2 diabetes.

Diabetes :: Vitamin B1 deficiency key to vascular problems for diabetic patients

Researchers at Warwick Medical School, University of Warwick, have discovered that deficiency of thiamine — vitamin B1 — may be key to a range of vascular problems for people with diabetes. They have also solved the mystery as to why thiamine deficiency in diabetes had remained hidden until now.

Diabetes :: Takeda responds to the FDA advisory committee recommendation

Following a joint meeting of the US Food and Drug Administration Endocrinologic and Metabolic Drugs Advisory Committee and the Drug Safety and Risk Management Advisory Committee, Takeda Global Research & Development underscores its position that ACTOS (pioglitazone HCl) offers a proven safety profile regarding the risk of cardiovascular disease.