Diabetes :: Older Diabetes Drugs Have Similar or Superior Effects to Newer, Pricier Medications

A review of published literature about benefits and harms of oral drugs for type 2 diabetes mellitus found that older agents, such as second-generation sulfonylureas and metformin, have similar or superior effects on glycemic control, lipids and other intermediate endpoints compared to newer, more expensive drugs, such as thiazolidinediones, alpha-glucosidase inhibitors and meglitinides.

Diabetes :: Most diabetes drugs provide similar glucose control

Most oral medications prescribed for type 2 diabetes are similarly effective for reducing blood glucose, but the drug metformin is less likely to cause weight gain and may be more likely than other treatments to decrease so-called bad cholesterol, according to a report funded by the Department of Health & Human Services’s (HHS) Agency for Healthcare Research and Quality (AHRQ).

Diabetes :: Older low-cost drugs are best buys for type 2 diabetes

Newer prescription drugs to treat type 2 diabetes ? including much-promoted Avandia and Actos ? are no more effective or safe than older drugs and cost significantly more, according to the latest report from Consumer Reports Best Buy Drugs, a public information project of Consumers U nion.

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