Heart Disease :: Ranexa, ranolazine – for treating chronic angina – chest pain

The Food and Drug Administration (FDA) announced the approval of Ranexa (ranolazine), a new drug for the treatment of chronic angina. Ranexa, a new molecular entity (NME), is the first drug approved to treat chronic angina in over ten years. Although several pharmacological activities of ranolazine have been described, the precise way the drug works is not fully understood. Because Ranexa affects electrical conduction in the heart (prolong the QT interval), it should only be used by patients who have not responded to other anti-anginal (long-acting nitrates, calcium channel blockers and beta blockers) drugs.

Intestinal Obstruction :: A case of intestinal obstruction – Acalypha Indica

Mrs. Kalawati, around 58 years old, was brought to me by her daughter on 18-01-05 in great distress with a severely distended abdomen. She had not passed stool since about a week and on asking also said that she had not passed any gas since few days though she had tried all sorts of churans for it. She had a constant feeling of rumbling in abdomen and had no appetite or thirst. If she were fed forcefully she would throw up. I suspected intestinal obstruction from the presentation.