Cancer :: Alternative Phase II Trial Design Could Reduce Phase III Failures
An alternative design for phase II cancer clinical trials may improve success rates for new cancer drugs in phase III trials.
Drug :: Microenvironment of Tumors Plays Role in Drug Resistance
The difficulty in penetrating tumors and reaching all of the cancer cells is an important but under-appreciated cause of drug resistance in solid tumors, according to a review article.
Stem Cell :: Destemming Stem Cells
In a commentary, Richard Hill, Ph.D., of the University of Toronto and Roberto Perris, Ph.D., of the University of Parma in Italy discuss the need for a more accurate definition of cancer stem cells.
Liver :: Mixing large doses of both acetaminophen painkiller and caffeine may increase risk of liver damage
Consuming large amounts of caffeine while taking acetaminophen, one of the most widely used painkillers in the United States, could potentially cause liver damage, according to a preliminary laboratory study reported in the Oct. 15 print issue of ACS’ Chemical Research in Toxicology, a monthly journal.
Alzheimer’s Disease :: Exelon first skin patch therapy to treat Alzheimer’s disease
The European Commission has approved Exelon® patch (rivastigmine transdermal patch), an innovative way to deliver this effective medicine to patients suffering from mild to moderately severe Alzheimer’s disease.
Surgery :: Basic surgery training to save lives and prevent disability
WHO is expanding its programme to train health care staff in low- and middle-income countries in essential emergency, basic surgery and anaesthesia skills. The programme, which already exists in 22 countries, will boost the capacity of first-level health facilities (rural or district hospitals and health centres) to deal with simple but essential surgery in a growing number of developing regions.
Salmonella :: MCP recalls all Queso Cincho de Guerrero produced by Quesos Sabrosos Mexicanos
MCP is recalling the “Queso Cincho de Guerrero” produced by “Quesos Sabrosos Mexicanos” because it has the potential to be contaminated with Salmonella, an organism which can cause serious and serious and sometimes infections in young children, frail or elderly people and others with weakened immune systems.
Epilepsy :: GSK’s Lamictal extended-release tablets for epilepsy
GlaxoSmithKline (NYSE: GSK) announced that the U.S. Food and Drug Administration (FDA) has issued an approvable letter for the new drug application (NDA) for Lamictal®XR™ (lamotrigine) Extended-Release Tablets.
Brain :: Rochester Investigating Blood Test for Concussions
The University of Rochester Medical Center received $1.5 million to develop a blood test for concussions by isolating proteins that can predict memory loss, chronic headaches or other neurological problems.
Autism :: Autism symptoms can improve into adulthood
Hallmarks of autism are characteristic behaviors — repetitive motions, problems interacting with others, impaired communication abilities — that occur in widely different combinations and degrees of severity among those who have the condition.