Circumcision :: Adult Male Circumcision Significantly Reduces Risk of Acquiring HIV

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced an early end to two clinical trials of adult male circumcision because an interim review of trial data revealed that medically performed circumcision significantly reduces a man’s risk of acquiring HIV through heterosexual intercourse.

HIV :: Male circumcision reduces HIV AIDS risk

A University of Illinois at Chicago study has been stopped early due to dramatic preliminary results indicating that medical circumcision reduces the risk of acquiring HIV during heterosexual intercourse by 53 percent.

Botulinum :: How botulinum toxin attaches to nerve cells – explained

A group of researchers, funded in part through two of NIAID’s Regional Centers of Excellence for Biodefense and Emerging Infectious Diseases, has provided a rare atomic glimpse of the initial step one of botulinu’s toxins takes to gain entry into human neurons. In an advanced online publication of the journal Nature, the scientists show structurally how botulinum neurotoxin B (one of seven toxins the bacterium produces) recognizes receptors on the surface of human neurons.

Breast Cancer :: Restoring Tamoxifen Sensitivity in Resistant Breast Cancer

The widely used breast cancer drug tamoxifen (Nolvadex?), which can become less effective over time, might retain its full strength indefinitely if used along with a second drug, according to new research in mice conducted by investigators from the National Cancer Institute (NCI), part of the National Institutes of Health, and their partners. The results appear in the December 11, 2006, issue of Cancer Cell.

Progress against lung disease attacking women in childbearing years

Researchers are advancing against a rare, deadly lung disease (related to hormones) that no one had even heard of a decade ago. The disease targets only women, striking them down during their childbearing years. It can be triggered by pregnancy, progresses rapidly, and often results in death within 10 years.

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