HIV :: p21 stops HIV-1 in its tracks in hematopoietic stem cells

Hematopoietic stem cells (HSCs) are one of the few cell types able to resist infection with HIV-1 despite expressing the cell surface molecules to which HIV-1 binds before entering a cell. In a study that appears in the February issue of the Journal of Clinical Investigation, researchers from Harvard Medical School, Boston, show that HSC expression of a protein known as p21Waf1/Cip1/Sdi1 (p21) is required for HSCs to be resistant to infection with HIV-1.

Flu :: HHS unveils two new efforts to advance pandemic flu preparedness

The Department of Health and Human Services (HHS) and its Centers for Disease Control and Prevention (CDC), in cooperation with departments and agencies across the Federal Government, announced two new efforts designed to improve state, local and community preparedness for an influenza pandemic, which can occur when a new strain of flu appears for which people have no immunity, and disease spreads rapidly around the world.

Influenza :: Release of influenza viruses for pandemic influenza vaccine development

Vaccines are a critical intervention for preventing influenza and reducing its health consequences during a pandemic. Since 2004, WHO has been working with various partners to find ways to improve and promote the development and production of pandemic vaccines in order to make such vaccines available rapidly and in as large a quantity as possible.

Bird Flu :: Bird flu pandemic mitigation

The best protection against pandemic influenza?a vaccine that is well-matched to the virus causing illness?is not likely to be available at the outset of a pandemic.

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