Hepatitis :: Acute Viral Hepatitis Cases Down in US

The three most common forms of acute viral hepatitis in the United States ? hepatitis A, B and C ? declined dramatically between 1995 and 2005, with hepatitis A and B at the lowest levels ever recorded since the government began collecting surveillance data more than 40 years ago, according to the Centers for Disease Control and Prevention (CDC). Hepatitis B and C are diseases that can lead to liver cancer and death.

HIV :: Risk of HIV transmission highest early in infection

New evidence suggests that the risk of HIV transmission may be highest in the early stages of infection. According to a study published in the April 1 issue of the Journal of Infectious Diseases, now available online, early infection accounted for nearly half of all transmission occurrences in an HIV-infected population in the province of Quebec, Canada.

Influenza :: GSK’s pre-pandemic influenza vaccine protects against H5N1

GlaxoSmithKline (GSK) announces clinical trial data from two new studies, which show, for the first time, that GSK?s candidate pre-pandemic split antigen H5N1 vaccine, formulated with GSK?s proprietary adjuvant system, provides a substantial level of cross-immunity against a ?drifted? (diverse) strain of H5N1.

HIV :: Pfizer’s Maraviroc significantly reduces viral load in HIV patients

At this week’s major HIV/AIDS research meeting, Pfizer presented pivotal data of its experimental medicine, maraviroc, which tackles HIV in an entirely new way. A 24 week analysis showed that approximately twice as many patients receiving maraviroc with an optimized background regimen achieved undetectable virus in the blood than if an optimized regimen was given alone.

HIV :: Merck’s Isentress in combination with OBT well tolerated

Results from two ongoing Phase III studies of ISENTRESS? (raltegravir), an investigational oral integrase inhibitor, demonstrated significantly greater antiretroviral activity of ISENTRESS when used in combination with optimized background therapy (OBT) versus placebo plus OBT in treatment-experienced HIV-infected patients who had failed antiretroviral therapies (ARTs), and who had HIV virus resistant to at least one drug in each of the three available classes of oral ARTs.

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