Stem Cell :: U-M researchers dispute widely held ideas about stem cells

How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? For more than three decades, many scientists have argued that the “immortal strand hypothesis” – which states that adult stem cells segregate their DNA in a non-random manner during cell division — explains it. And several recent reports have presented evidence backing the idea.

Rheumatoid Arthritis :: Biologic treatment for rheumatoid arthritis and the risk of cancer

Findings of various clinical trials and observational studies conflict over the risk of malignancy related to the use of tumor necrosis factor alpha blockers. The relationship between rheumatoid arthritis (RA), an autoimmune disease marked by chronic inflammation of the joints and tissue surrounding vital organs, and the incidence of cancer is complicated.

Smoking :: Smoking turns on genes permanently

Smoking tobacco is no longer considered sexy, but it may prove a permanent turn on for some genes. Research published today in the online open access journal BMC Genomics could help explain why former smokers are still more susceptible to lung cancer than those who have never smoked.

HIV :: High-risk behaviors could lead to HIV epidemic in Afghanistan

In a report that is among the first to describe the prevalence of HIV and Hepatitis B and C viruses in Afghanistan, a researcher from the University of California, San Diego (UCSD) School of Medicine voiced concerns that increasing injection drug use and accompanying high-risk behavior could lead to an HIV epidemic in Afghanistan.

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