Infection :: New drug design targets a large range of bacterial and fungal infections

The “resistance movement” founded by bacteria to combat antibiotics may be losing ground. By combining key properties of two different types of weapons used by the innate defense systems of organisms, a team of scientists at the Weizmann Institute of Science has managed to design a more powerful weapon, hoping that this will provide a basis for novel and more effective antibiotics.

Hemophilia :: Spleen tissue transplant cures hemophilia

In hemophilia, a mutated gene prevents the production of a blood-clotting protein. Treatments for hemophilia and other genetic diseases may consist of risky blood transfusions or expensive enzyme replacement therapy. But what if the body could be induced to begin producing these proteins by transplanting healthy tissue with the abilities that are lacking? The Weizmann Institute’s Immunology Department showed how such a transplant might be made feasible.

Healthcare :: Medical teams are key to patient safety

Medical teams — not individuals — are critical to the prevention of catheter-related bloodstream infections, as well as for the overall health, safety, and welfare of patients, according to an editorial by two Virginia Commonwealth University physicians published in today’s issue of the New England Journal of Medicine.

Cancer :: New drug targets for cancer therapies

Solving a 100-year-old genetic puzzle, researchers at the UCSD School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor. Their findings could lead to new drug targets for cancer therapies.

Healthcare :: Safer ICUs – Cheap, simple, low-tech steps work

Hospitals will quickly slash the rate of common, costly and potentially lethal catheter-related bloodstream infections in their intensive care units (ICUs) by using cheap, low-tech, common-sense measures like hand washing, timely removal of unneeded catheters and use of sites other than the groin to place lines when possible, according to a report from safety experts at Johns Hopkins in the Dec. 28 issue of the New England Journal of Medicine.

Gene :: Complexity Constrains Evolution of Human Brain Genes

Despite the explosive growth in size and complexity of the human brain, the pace of evolutionary change among the thousands of genes expressed in brain tissue has actually slowed since the split, millions of years ago, between human and chimpanzee, an international research team reports in the December 26, 2006, issue of the journal, PLOS Biology.

Video Games :: Video games are hard to give up

Kids and adults will stay glued to video games this holiday season because the fun of playing actually is rooted in fulfilling their basic psychological needs. Psychologists at the University of Rochester, in collaboration with Immersyve Inc., a virtual environment think tank, asked 1,000 gamers what motivates them to keep playing. The results published in the journal Motivation and Emotion this month suggest that people enjoy video games because they find them intrinsically satisfying.

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