Cholesterol :: New therapy to treat severely elevated cholesterol levels

Researchers at the University of Pennsylvania School of Medicine have demonstrated the potential of a new type of therapy for patients who suffer from high cholesterol levels. The findings are in the January 11 issue of the New England Journal of Medicine (NEJM). In this study, patients with homozygous familial hypercholesterolemia (FH), a high-risk condition refractory to conventional therapy, had a remarkable 51 percent reduction in low-density lipoprotein (LDL) or “bad cholesterol” levels.

Caffeine :: Caffeine cuts post-workout pain by nearly 50 percent

Although it’s too soon to recommend dropping by Starbucks before hitting the gym, a new study suggests that caffeine can help reduce the post-workout soreness that discourages some people from exercising. In a study to be published in the February issue of The Journal of Pain, a team of University of Georgia researchers finds that moderate doses of caffeine, roughly equivalent to two cups of coffee, cut post-workout muscle pain by up to 48 percent in a small sample of volunteers.

DNA :: Spanish scientists reveal dynamic map of proteins

Scientists from the Institute for Research in Biomedicine (IRB Barcelona), the Life Sciences Program at the Barcelona Supercomputing Center (BSC) and the National Institute for Bioinformatics (INB) have published a provisional “atlas” of the dynamic behaviour of proteins in the prestigious scientific journal, Proceedings of the National Academy of Sciences.

Cancer :: Turning green gunk to gold, anti-cancer gold

Combining synthetic chemistry techniques with a knowledge of the properties and actions of enzymes, scientists have been able to produce an exciting class of anti-cancer drugs originally isolated from blue-green algae.

Health Care :: Hopeful nurses are more comfortable, condident in caring for dying children

Nurses with higher levels of hopefulness are more likely to report feeling confident and competent in their ability to care for dying children and their families. Based on a survey of hundreds of pediatric nurses, researchers found that nurses who were more confident about their skills also were more likely to have received education in palliative care — the practice of providing high-quality, responsive care to patients with a life-threatening illness.

Tumor :: Homing nanoparticles pack multiple assault on tumors

Researchers have developed nanoparticles that seek out tumors and bind to their blood vessels, and then attract more nanoparticles to the tumor target. Using this system they demonstrated that the homing nanoparticle could be used to deliver a “payload” of an imaging compound, and in the process act as a clotting agent, obstructing as much as 20 percent of the tumor blood vessels.

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