A prominent problem in AIDS is a form of dementia that robs one?s ability to concentrate and perform normal movements. Scientists at the Burnham Institute for Medical Research (Burnham) have discovered how HIV/AIDS disrupts the normal replication of stem cells in the adult brain, preventing new nerve cells from forming.
New evidence reported in the August issue of Cell Stem Cell, a publication of Cell Press, offers a novel perspective on how the HIV/AIDS virus leads to learning and memory deficits, a condition known as HIV-associated dementia.
In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as ?queens,? possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the ?worker? cells that form the bulk of the tumor.
Researchers from the Stem Cell Transplant Program and the Amyloid Treatment and Research Program at Boston University Medical Center (BUMC) have found that high-dose chemotherapy and blood stem cell transplantation can result in long-term survival for patients diagnosed with primary systemic light chain (AL) Amyloidosis.
When it comes to generating neurons, researchers have found that not all embryonic stem (ES) cell lines are equal. In comparing neurons generated from two NIH-approved embryonic stem cell lines, scientists have uncovered significant differences in the mature, functioning neurons generated from each line.
A report from researchers at Children’s Hospital Boston and the Harvard Stem Cell Institute sheds new light on a now-discredited Korean embryonic stem cell line, setting the historical record straight and also establishing a much-needed set of standards for characterizing human embryonic stem cells. The report was published online August 2 by the journal Cell Stem Cell.
One of six Autism Centers of Excellence (ACE) in the country has been established at the University of California, San Diego by the National Institutes of Health (NIH), to be directed by Eric Courchesne, Ph.D., professor of neurosciences at the UC San Diego School of Medicine and a leading expert on brain abnormalities associated with autism, a brain disorder affecting an estimated two million people in the U.S. The symptoms are impaired social, emotional, language and cognitive development.
Can a genetic signature identify the origin of a human stem cell line? Scientists report that a widely available method for comprehensive genetic analysis can help distinguish the type of human embryo that stem cells come from.
A new study suggests that acute leukemia patients whose cancer cells show a genetic change that usually predicts a swift return of the disease following remission may remain disease-free longer when given aggressive therapy.
A special type of cell found in the eye has been found to be very important in regenerating the retina in zebrafish and restoring vision even after extensive damage.