A drug that shuts down a critical cell-signaling pathway in the most common and aggressive type of adult brain cancer successfully kills cancer stem cells thought to fuel tumor growth and help cancers evade drug and radiation therapy, a Johns Hopkins study shows.
World renowned experts on motor neurone disease will share their work at an international symposium hosted by the University of Edinburgh to enable greater understanding of the condition.
How do adult stem cells protect themselves from accumulating genetic mutations that can lead to cancer? For more than three decades, many scientists have argued that the “immortal strand hypothesis” – which states that adult stem cells segregate their DNA in a non-random manner during cell division — explains it. And several recent reports have presented evidence backing the idea.
Some scientific results are hard to spot, especially in genetic research. Often scientists are unable to physically see if the gene they inserted into a cell has produced the desired trait.
A mosquito-borne disease often known as ?break-bone fever? has found a new enemy in a unique type of mouse.
Geron Corporation (Nasdaq: GERN) today reported its scientists and collaborators have demonstrated that human embryonic stem cell (hESC)-derived cardiomyocytes improve heart function when transplanted after myocardial infarction.
When human heart muscle cells derived from embryonic stem cells are implanted into a rat after a heart attack, they can help rebuild the animal’s heart muscle and improve function of the organ, scientists report in the September issue of Nature Biotechnology.
Working with embryonic mouse brains, a team of Johns Hopkins scientists seems to have discovered an almost-too-easy way to distinguish between ?true? neural stem cells and similar, but less potent versions.
Cancer stem cell researchers at the James P. Wilmot Cancer Center at the University of Rochester Medical Center have received grants totaling $1.7 million to pursue the study of experimental therapies that target leukemia stem cells.
Researchers at BRIC, University of Copenhagen, have identified a new gene family (UTX-JMJD3) essential for embryonic development. The family controls the expression of genes crucial for stem cell maintenance and differentiation, and the results may contribute sig-nificantly to the understanding of the development of cancer.