Immunity :: Mathematicians help unlock secrets of the immune system

A group of scientists, led by mathematicians, has taken on the challenge of building a common model of immune responses. Their work will radically improve our understanding of the human immune system by allowing all the scientific disciplines working on it to have a common reference point and language.

Ultrasound :: Transcutaneous cervical esophageal ultrasound can not substitute for 24-h pH monitoring or manometry

Gastroesophageal reflux arises from increased exposure and/or sensitivity of the esophageal mucosa to gastric contents, and affects 5-40 percent of the population. Esophageal ultrasound studies in GER have mainly focused on the evaluation of the gastroesophageal junction and esophageal motility performed by transabdominal or endoluminal routes. Visualizing refluxate in transcutaneous cervical esophageal ultrasound was found to be useful as a pre-diagnostic tool for estimating GER and/or manometric pathology in 71.1 percent of adults.

Nobel Prize :: Professor Sir Martin Evans wins Nobel Prize for Medicine

Professor Sir Martin Evans, Professor of Mammalian Genetics at the School of Biosciences, Cardiff University, has won the 2007 Nobel Prize for Medicine. The Nobel Assembly at the Karolinska Institute, Sweden, announced this morning that Professor Sir Martin was one of three winners for “a series of ground-breaking discoveries concerning embryonic stem cells and DNA recombination in mammals.”

Clinical Trial :: Paving the way for future pan-European clinical trials

Pan-European collaboration is important for many clinical trials and essential for trials that are investigating treatments for rare diseases. That was the message delivered today by the European Medical Research Councils (EMRC), the membership organisation for medical research councils across Europe based at the European Science Foundation (ESF) in Strasbourg, which is coordinating two trials in rare diseases and about to launch a review of how best to implement clinical trials that are initiated by investigators.

Depression :: Anti-depressant drugs can double risk of gastrointestinal bleeding

New research shows that selective serotonin reuptake inhibitors (SSRIs), a group of drugs commonly used to treat depression, may double the risk of gastrointestinal bleeding, according to researchers from Wake Forest University School of Medicine and colleagues. When the drugs are taken with aspirin and other similar pain medications, the risk is more than 600 percent higher.

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