Non-steroidal anti-inflammatory drug increases liver damage in mice carrying mutant human gene

Research performed at Washington University School of Medicine in St. Louis sheds light on the mechanisms that contribute to liver disease in alpha-1-AT deficiency patients. People with alpha-1-deficiency have a genetic mutation that can lead to emphysema at an early age and to liver damage. Using an experimental mouse model of the disorder, the researchers investigated the effects of a non-steroidal anti-inflammatory drug on liver injury.

Immunity :: New light shed on immune system development

Research led by King’s scientists, and published online in the journal Nature, sheds new light on the development of the immune cells which are critical in fighting infection and some tumours. It may also provide clues to the mystery of why autoimmune diseases in women often go into remission during pregnancy.

Silver bullet – UGA researchers use laser, nanotechnology to rapidly detect viruses

Using nanotechnology, a team of University of Georgia researchers has developed a diagnostic test that can detect viruses as diverse as influenza, HIV and RSV in 60 seconds or less. In addition to saving time, the technique — which is detailed in the November issue of the journal Nano Letters — could save lives by rapidly detecting a naturally occurring disease outbreak or bioterrorism attack.

Gene :: Dartmouth researchers identify a gene that enhances muscle performance

A team of researchers, led by scientists at Dartmouth Medical School and Dartmouth College, have identified and tested a gene that dramatically alters both muscle metabolism and performance. The researchers say that this finding could someday lead to treatment for muscle diseases, including helping the elderly who suffer from muscle deterioration and improving muscle performance in endurance athletes.

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