Health :: Possible new strategy for treating rare muscle disease, kidney disorders

Based on clues provided by a study with transgenic mice, a research group at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), has developed a strategy that will be tested as the first treatment for people with hereditary inclusion body myopathy (HIBM), a rare, degenerative muscle disease.

Stem Cell :: Reprogrammed fibroblasts identical to embryonic stem cells

Embryonic stem cells are unique because they can develop into virtually any kind of tissue type, an attribute called pluripotency. Somatic cell nuclear transfer (?therapeutic cloning?) offers the hope of one day creating customized embryonic stem cells with a patient?s own DNA. Here, an individual?s DNA would be placed into an egg, resulting in a blastocyst that houses a supply of stem cells. But to access these cells, researchers must destroy a viable embryo.

Diabetes :: New drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online at Nature on June 6, 2007.

Diet :: Dietary preferences and patterns may be linked to genes

The relative amount of protein, carbohydrate, and fat that people choose to eat may be influenced by genetics, according to new research. Jose Ordovas, PhD, director of the Nutrition and Genomics Laboratory at the Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University (USDA HNRCA), and colleagues found that the apolipoprotein A-II gene (APOA2) is associated with proportions of fat, carbohydrate, and protein in the diet, along with total calories and, therefore, with body-mass-index (BMI).

Bipolar Disorder :: Brain holds clues to bipolar disorder

Looking into the brain is yielding vital clues to understanding, diagnosing and treating bipolar disorder, according to findings being presented today at the Seventh International Conference on Bipolar Disorder. Two studies, featured in a press briefing held at 12:15 p.m., Thursday, June 7, have helped to identify novel pathways and markers for diagnosis and treatment of the disease.

Fever :: New bacterium discovered related to cause of trench fever

A close cousin of the bacterium that debilitated thousands of World War I soldiers has been isolated at UCSF from a patient who had been on an international vacation. The woman, who has since recovered, suffered from symptoms similar to malaria or typhoid fever, two infections that can occur in returning travelers.

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