Research investigators have identified molecular changes in multiple myeloma cells that activate an important biological pathway associated with cell growth and survival, thereby revealing potential new targets for drugs to treat this cancer.
Not all patients with sepsis mount the same immune response, even when they look the same clinically, according to findings from the first large-scale natural history study of sepsis.
Mouse mammary glands deficient in PPAR?, a nuclear receptor that regulates the storage of fat, produce toxic milk that causes inflammation and baldness in suckling pups, report scientists at the Salk Institute for Biological Studies.
The number of men in the United States with undiagnosed diabetes has declined sharply over the past 25 years, with Hispanics and African-Americans no longer more likely than whites to unknowingly have the disease, according to a RAND Corporation study issued today.
A newly developed DNA vaccine appears safe and may produce beneficial changes in the brains and immune systems of individuals with multiple sclerosis, according to an article posted online today that will appear in the October 2007 print issue of Archives of Neurology, one of the JAMA/Archives journals.
In some ways, certain tumors resemble bee colonies, says pathologist Tan Ince. Each cancer cell in the tumor plays a specific role, and just a fraction of the cells serve as ?queens,? possessing the unique ability to maintain themselves in an unspecialized state and seed new tumors. These cells can also divide and produce the ?worker? cells that form the bulk of the tumor.
Scientists are trying a plumber?s approach to rid the brain of the amyloid buildup that plagues Alzheimer?s patients: Simply drain the toxic protein away.
An Indonesian woman aged 29 years died this weekend on the island of Bali. Samples have tested positive for bird flu after an initial test, officials reported.
Abbott has received a supplemental Premarket Approval from the U.S. Food and Drug Administration for its recently introduced RealTime HIV-1 viral load test.
Antioxidants are widely considered an important defense against heart disease, but University of Utah researchers have found excessive levels of one antioxidant?reduced glutathione?actually may contribute to the disease.