Insulin

Diabetes :: Glucose levels trigger compensation for type 2 diabetics

Many individuals with type 2 diabetes are diabetic because the cells of their body no longer respond to the hormone insulin, which is crucial for lowering blood sugar levels (blood glucose levels). However, before individuals become clinically diabetic their body tries to compensate for the increasing resistance to the effects of insulin by increasing both the amount of insulin secreted and the mass of insulin-secreting cells (beta cells) in the pancreas.

Brain :: High-normal uric acid linked with mild cognitive impairment in the elderly

Researchers at the Johns Hopkins and Yale university medical schools have found that a simple blood test to measure uric acid, a measure of kidney function, might reveal a risk factor for cognitive problems in old age. Of 96 community-dwelling adults aged 60 to 92 years, those with uric-acid levels at the high end of the normal range had the lowest scores on tests of mental processing speed, verbal memory and working memory.

Diabetes :: Japan’s Otsuka to develop saxagliptin for type 2 diabetes

Bristol-Myers Squibb Company (NYSE: BMY) and Otsuka Pharmaceutical Co., Ltd. announced Otsuka has been granted exclusive rights in Japan to develop and commercialize the investigational compound saxagliptin, being studied for the treatment of Type 2 diabetes. Saxagliptin, discovered by Bristol-Myers Squibb, is a dipeptidyl peptidase-4 (DPP-4) inhibitor currently in Phase III development in the United States and Europe.

Diabetes :: Safety warning about blood glucose meters

The Medicines and Healthcare products Regulatory Agency (MHRA) has identified a safety problem with certain blood glucose meters which under certain conditions display the wrong units of measurement. This could result in an insulin overdose and hypoglycaemic coma.

Diabetes :: Less sugary drinks during childhood may cut disease risk

Symptoms of heart disease and diabetes usually seen in adults are increasingly being found in adolescents according to a longitudinal study, which suggests that reducing the intake of sugar-sweetened beverages during childhood may lessen the risk of chronic disease in later life.

Acromegaly :: Options improving for patients with acromegaly and gigantism – endocrinology expert

Scientific, technological and medical advances made in the past two decades are leading to more definitive diagnoses, earlier and more effective treatment options and better outcomes for patients suffering from a condition called acromegaly, according to an article published in today’s issue of the New England Journal of Medicine and authored by a specialist in endocrinology at Cedars-Sinai Medical Center.

Diabetes :: Alert on Counterfeit One Touch Blood Glucose Test Strips

The U.S. Food and Drug Administration (FDA) is providing an update to its notifications on October 13, and October 23, 2006, alerting the public to counterfeit blood glucose test strips being sold in the US for use with various models of LifeScan, Inc., One Touch Brand Blood Glucose Monitors. These test strips are used by people with diabetes to measure their blood glucose. Today?s update includes an additional lot number that is being distributed, along with a description of how to identify the new lot.

Diabetes :: Linchpin discovered in insulin metabolism

Scientists at the University of Bonn have identified a new gene which could play an important role in the development of diabetes. Flies in which this hereditary factor is defective are also significantly smaller than other members of their species and live appreciably longer. In the current issue of the prestigious journal Nature the Bonn researchers have published two articles on this topic.

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