Natural compounds derived from a sea anemone extract and a shrub plant have been found to block the autoimmune disease response in type-1 diabetes and rheumatoid arthritis, according to University of California, Irvine researchers.
Scientists at Children’s Hospital of Pittsburgh of UPMC have identified a protein that is critical to the development of inflammation during lung infection in patients with cystic fibrosis. The identification of this protein, called interleukin-23, is an important finding that gives researchers a specific target for developing new therapies.
Magnetic resonance imaging (MRI) could become a valuable tool for predicting the risk of muscle injury during and following radiation therapy, according to investigators at St. Jude Children’s Research Hospital.
A study published in the New England Journal of Medicine shows that treatment for periodontal disease in pregnant women does not result in a lower rate of adverse pregnancy outcomes such as preterm birth and low birth weight. At the same time, the study showed that periodontal treatment during pregnancy is safe. The researchers recommend additional studies to assess the potential benefits of the treatment.
University of Manchester researchers are recruiting people with backache caused by nerve root pain — commonly known as sciatica — in the first ever study to discover if therapeutic ultrasound can help their condition.
Just a small fraction of patients who have a stroke receive the only drug — TPA — available to treat the condition. Now doctors and scientists at the University of Rochester Medical Center have developed a potential new treatment that will reach a milestone in the next few months, when the experimental treatment is tested for the first time in people who have suffered a stroke or “brain attack.”
Chemicals commonly used to treat heartburn also display fighting power against the oral bacteria linked with gum disease, according to researchers at the University of Rochester Medical Center and G?teborg University in Sweden.
Researchers have identified three proteins that appear to be highly predictive of chronic lung rejection up to 20 months before the rejection occurred. Lung transplants are a common therapy for many end-stage lung diseases such as chronic obstructive pulmonary disease, cystic fibrosis and pulmonary hypertension. If doctors can predict which patients are beginning to reject the transplanted organ, they could try to head it off.
Researchers have found a highly unusual distribution of two proteins in the lungs and airways of people with cystic fibrosis, a discovery that could be a step in determining how the disease progresses. The proteins, first uncovered as a result of the human genome project, are thought to play a role in the body’s immune system.
With the help of some high tech equipment, well-defined mouse models and analytical know how, researchers are trying to understand why a flu virus kills some people but not others. Studies to be presented at “Physiological Genomics and Proteomics of Lung Disease” found that a strain of mice more likely to die of influenza infection mounts a dramatically enhanced immune response in the lungs compared to a strain of mice that generally develops milder disease.