Liver :: Liver fibrosis will be treated by a potential target

The outcome of hepatitis is either self recovery or its development into liver fibrosis or, further, liver cirrhosis. Liver fibrosis is the early pathological process of cirrhosis, which is considered a reversible, wound-healing response. Since no ideal drug is available for its therapy, liver fibrosis is currently considered to be a major worldwide health problem.

Drug :: Computational modeling could improve antibody drugs

Scientists have developed computational models that could improve the effectiveness of drugs based on antibodies. By calculating which molecular changes would cause the antibodies to bind more tightly to their targets, the models already have helped create a new version of an anticancer drug.

HIV :: FDA approves new HIV drug raltegravir tablets

The U.S. Food and Drug Administration (FDA) has approved raltegravir tablets for treatment of Human Immunodeficiency Virus (HIV)-1 infection in combination with other antiretroviral agents in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

Health :: Study reveals a key to blood vessel growth and possible drug target

Researchers have identified a molecular pathway that plays a critical role in the growth of blood vessels. The finding not only offers an important insight into the development of the vascular system during embryonic development but suggests a potential target for inhibiting the blood vessels that fuel cancers, diabetic eye complications and atherosclerosis, the researchers say.

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