Cancer :: Genes associated with cancer drug resistance
Scientists at the National Cancer Institute (NCI), a part of the National Institutes of Health, have created a database of information about a group of genes associated
with multidrug resistance in cancerous tumors. The research, published in the issue of “Cancer Cell”, details the gene expression of a 48-member family of proteins called ABC transporters. The NCI scientists identified associations between expression of individual ABC transporters in cancer cells and resistance to specific drugs.