Brain :: Brain damaging amoeba linked to 6 deaths

US health officials reported that an amoeba that typically lives in lakes and enters the body through the nose and attacks the brain has been linked to six deaths in the United States this year.

Even though encounters with the single-celled organism are rare, it has killed six boys and young men this year. The increase in cases has health officials concerned, with predictions of more cases in the future.

“This is a heat-loving amoeba. As water temperatures go up, it does better,” Michael Beach, a specialist in recreational waterborne illnesses for the U.S. Centers for Disease Control and Prevention, told the news service the AP. “In future decades, as temperatures rise, we’d expect to see more cases.”

According to the CDC, the amoeba is called Naegleria fowleri, and it killed 23 people in the United States from 1995 to 2004. But health officials have noticed a rise in cases this year, with three in Florida, two in Texas and one in Arizona. The CDC knows of only several hundred cases worldwide since the microscopic bug’s discovery in Australia in the 1960s.

Though infections tend to be found in southern states, Naegleria lives almost everywhere in lakes, hot springs, even dirty swimming pools, subsisting off algae and bacteria in the sediment. People become infected when they wade through shallow water and stir up the bottom.

Infection with Naegleria causes the disease primary amebic meningoencephalitis (PAM), a brain inflammation, which leads to the destruction of brain tissue.

Initial signs and symptoms of PAM start 1 to 14 days after infection. These symptoms include headache, fever, nausea, vomiting, and stiff neck. As the amebae cause more extensive destruction of brain tissue this leads to confusion, lack of attention to people and surroundings, loss of balance, seizures, and hallucinations. After the onset of symptoms, the disease progresses rapidly and usually results in death within 3 to 7 days.

Several drugs are effective against Naegleria in the laboratory. However, although a variety of treatments have been used to treat infected persons, their effectiveness is unclear since most infections have still been fatal.


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