Obesity :: Increased cardiometabolic risk in obesity

Obesity and its many related health hazards have become a serious and growing problem worldwide. While environmental and lifestyle factors play a key role in the development of obesity, genetic variation may determine an individual’s susceptibility to weight gain and to the rise of obesity-related health risks.

Diabetes :: Elucidation of the genome for diabetics with DNA chips

A CNRS team headed by Philippe Froguel (CNRS, University of Lille 2, Pasteur Institute, Imperial College London) and Rob Sladek (McGill University, Montreal, Canada) in a French-British-Canadian collaboration that accounts for about 70 percent of the genetic risk for patients with type two diabetes.

Breast Cancer :: Breast cancer survival rates improved by novel drug sequence

Changing the way women are treated for breast cancer could improve their overall chance of survival, according to research published today in the Lancet. The new paper shows that switching to a drug called exemestane, two to three years after commencing standard therapy with the drug tamoxifen, can cut the risk of death for certain women by a further 17 percent compared with using tamoxifen alone.

Stent :: Efficacy of the CYPHER Sirolimus eluting coronary stent confirmed

The long-term safety of the CYPHER(R) Sirolimus-eluting Coronary Stent, specifically in terms of death, myocardial infarction (heart attacks) and stent thrombosis (also known as blood clots), is comparable to that of bare metal stents when used according to product labeling, according to a variety of studies appearing today in the New England Journal of Medicine (NEJM).

Obesity :: A chemical pathway that causes mice to overeat and gain weight

The Scripps Research team, led by neuroscientists Manuel Sanchez-Alavez and Tamas Bartfai, discovered that mice genetically altered to lack a molecule known as the EP3 receptor tend to be more active during their normal sleep cycle and to eat more. In the study, this led to weight increases of up to 30 percent relative to mice with the receptors.

Tobacco :: Adults support r-rating for movies showing tobacco

According to a new survey, 81 percent of adults in the United States agree adolescents are more likely to smoke if they watch actors smoke in movies. Also, 70 percent support a new R-rating for any movies with on-screen tobacco imagery, unless the film clearly demonstrates the dangers of smoking.

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