Asthma :: Intervention program reduces asthma in children

An asthma intervention program applied during the first year of life significantly reduced the prevalence of asthma in high risk children at 7 years of age, according to a new study featured on the online version of the Journal of Allergy & Clinical Immunology (JACI). The JACI is the peer-reviewed journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).

Allergy :: Day care facilities – source for indoor allergens

Day care facilities were shown to be an important source for allergen exposure, according to a study featured on the online version of the Journal of Allergy & Clinical Immunology (JACI). The JACI is the peer-reviewed journal of the American Academy of Allergy, Asthma & Immunology (AAAAI).

Smallpox :: Cancer Drug Slows Poxvirus in Mice

Mice given a relatively new cancer drug can survive an otherwise lethal dose of vaccinia virus, a relative of smallpox virus, report scientists supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health.

Allergy :: Food Allergy Research Consortium Focuses on Peanut Allergy

The only advice doctors can give to the 4 percent of Americans with potentially life-threatening food allergies is to avoid the culprit food, often nuts or shellfish. But that may change as researchers in a new Food Allergy Research Consortium, announced, strive to develop therapies to treat and prevent food allergy.

Tuberculosis :: Promising New TB Drug Enters Clinical Trial

A promising new drug candidate that may be effective against both actively dividing and slow-growing Mycobacterium tuberculosis (M. tb) has begun testing in humans, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, announced today. The novel antibiotic, PA-824, may shorten the time needed to treat tuberculosis (TB), a contagious disease that claims approximately two million lives worldwide each year. In partnership with the non-profit New York-based Global Alliance for TB Drug Development (TB Alliance), NIAID contributed to the drug candidate?s preclinical safety and efficacy testing in animal models. Now, a clinical trial to assess PA-824?s safety, sponsored by the TB Alliance, has opened at a medical clinic in Lincoln, NE.

Allergies :: Day care settings are a significant source of indoor allergens

Researchers studying day care facilities in the South have found the facilities to be a significant source for indoor allergen levels. A new study of 89 day care settings in two central North Carolina counties found detectable levels of seven common allergens from fungus, cats, cockroaches, dogs, dust mites, and mice in each facility tested. The levels were similar to those found in Southern homes.

HIV :: Human Cells Can Silence HIV Genes – RNA silencing

For the first time, scientists have shown that humans use an immune defense process common in plants and invertebrates to battle a virus. The new finding that human cells can silence an essential part of HIV?s genetic make-up could have important implications for the treatment of people infected with the virus. Led by Kuan-Teh Jeang, M.D, Ph.D., of the National Institute of Allergy and Infectious Diseases (NIAID), part the National Institutes of Health, the researchers published their findings in this week?s issue of the journal Immunity.

Immune System :: How disease bacterium survives inside immune system cell

New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists? belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections. A paper describing the research was released today online in The Journal of Immunology. Frank R. DeLeo, Ph.D., of Rocky Mountain Laboratories (RML), part of the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health, directed the work at RML, in Hamilton, MT, in collaboration with lead author Dori L. Borjesson, D.V.M., Ph.D., of the University of Minnesota in St. Paul.

Respiratory :: Excess oxygen worsens lung inflammation

Research performed at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has revealed that oxygen therapy aimed at helping mice with acute lung inflammation breathe paradoxically worsened their illness. The researchers say excess oxygen appears to thwart a natural process that limits lung tissue damage. They overcame this deleterious side effect, however, by adding an inhaled anti-inflammatory drug to the oxygen therapy.

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