BioCell Technologies has released the results of a bioassay which supports the effectiveness of its dietary ingredient BioCell Collagen II in preventing wrinkles.
The ingredient provides a matrix of bioavailable hyaluronic acid (HA, 10%), depolymerized chondoitin sulphate (20%) and collagen type II (60%).
HA is a glucosaminoglycan extracellular matrix constituent which occurs naturally in the human body up until the age of 30, after which levels start to decrease. This decrease is understood to play a large role in the aging process. Hence, hyaluronic acid is often used as an ingredient in both joint and skin health formulations.
Degradation of HA is thought to be the work of an enzyme called hyaluronidase.
The study, commissioned by AIBMR Life Sciences, showed that Biocell Collagen II inhibits hyaluronidase by between 250 and 4,000 micrograms/milliliter in vitro – up to 88 percent – depending on the concentration.
Alex Schauss, director of natural and medicinal products research at AIBMR said: “This finding provides in vitro evidence that BioCell Collagen II’s naturally ocurring combination of collagen and HA may promote skin health via enhancement of elasticity, possibly resulting in a reduction in wrinkles.”