The key to combating AIDS in Russia may be to treat HIV-infected drug users. A new model estimating the spread of HIV in Russia suggests that treating injection drug users with antiretroviral medication will slow transmission of the virus among the general population.
Even as the mosquito season draws to a close, Public Health ? Seattle & King County continues to find birds infected with West Nile virus. A dead crow found near downtown Kent on October 26th and tested at the Washington Animal Disease Diagnostic Laboratory last week was determined to be positive for West Nile virus. This is the sixth positive bird finding in King County since early October, and is an indication that the virus is likely spread throughout the region.
For the first time, researchers have inhibited the development of epilepsy after a brain insult in animals. By using gene therapy to modify signaling pathways in the brain, neurology researchers found that they could significantly reduce the development of epileptic seizures in rats.
Antiretroviral therapy can keep HIV infection in check and delay and ameliorate the symptoms of HIV/AIDS. However, the drugs do not manage to eradicate the virus completely; individuals have to stay on the drugs permanently. Preclinical studies in mice by Ekatarina Dadachova and colleagues (Albert Einstein College of Medicine) published in the international open-access journal PLoS Medicine now suggest a new strategy to locate and kill many if not all HIV-infected cells in the body.
Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi’s sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth. The finding, published in the most recent issue of PLoS Pathogens, offers new potential strategies for treating Kaposi’s sarcoma and other cancers associated with viruses
An estimated 50 million people were affected by zoonotics diseases, including H5N1 (bird flu), SARS and Rabies, between 2000 and 2005 and up to 78,000 died. No effective vaccines exist for the most common diseases. And the Dengue virus, which caused about a third of the deaths is experiencing a global resurgence. Zoonotic diseases can become serious killers if they adapt to human to human transmission — HIV and Measles are two examples.
Gene-base therapy may be effective against HIV, U.S. researchers report. An investigational gene-based immunotherapy called VRX496 suggests it can fight the virus, according to a phase I, open-label, non-randomized clinical trial conducted at the University of Pennsylvania School of Medicine.
Happiness and other positive emotions play an even more important role in health than previously thought, according to a study published in the journal Psychosomatic Medicine by Carnegie Mellon University psychology Professor Sheldon Cohen.
Novartis announced plans to build an integrated biomedical Research & Development center in Shanghai’s Zhangjiang Hi-Tech Park that will become an integral part of the Group’s global research and development network.
With the help of some high tech equipment, well-defined mouse models and analytical know how, researchers are trying to understand why a flu virus kills some people but not others. Studies to be presented at “Physiological Genomics and Proteomics of Lung Disease” found that a strain of mice more likely to die of influenza infection mounts a dramatically enhanced immune response in the lungs compared to a strain of mice that generally develops milder disease.