Cancer :: Dealing deadly cancers a knockout punch

New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers. Reovirus, a non-pathogenic virus under development at Calgary, Alberta-based Oncolytics Biotech, has shown powerful anti-cancer activity against cultured tumor cells, in animal models, and in human clinical trials. Oncolytics’ proprietary reovirus formulation, Reolysin?, is active against numerous cancers, including intractable sarcomas and melanomas.

HIV :: Imaging techniques reveal that HIV infects host cells using a molecular entry claw

An advanced imaging technique known as electron tomography has allowed researchers at the National Cancer Institute (NCI), part of the National Institutes of Health (NIH), to visualize an ?entry claw,? a unique structure formed between the human immunodeficiency virus (HIV) that causes AIDS and the cell it infects. The findings are in the May 4, 2007, issue of PLoS Pathogens.

Vaccine :: New vaccine could cure killer RSV infection

Respiratory syncytial virus (RSV) infection is a widespread infant illness that has been linked to asthma and can be deadly but may be curable by the development of this new vaccine technology by the Sir Albert Sakzewski Virus Research Centre and The University of Queensland’s Faculty of Biological and Chemical Sciences.

HPV :: HPV raises throat cancers risk

Researchers at the Johns Hopkins Kimmel Cancer Center have conclusive evidence that human papillomavirus (HPV) causes some throat cancers in both men and women. Reporting in the May 10 issue of the New England Journal of Medicine, the researchers found that oral HPV infection is the strongest risk factor for the disease, regardless of tobacco and alcohol use, and having multiple oral sex partners tops the list of sex practices that boost risk for the HPV-linked cancer.

Hepatitis C :: Hepatitis C increases risk of non-Hodgkin lymphoma

Hepatitis C infection is associated with an increased risk of non-Hodgkin lymphoma (malignancy involving lymphatic tissue) of 20 percent to 30 percent, and a three-fold increase in the risk of another type of lymphoma, according to a study in the May 9 issue of JAMA.

Influenza :: Why predicting the next influenza pandemic is difficult and how scientists can best prepare

In planning for a future influenza pandemic, most experts agree that two things are known for certain?there will be another pandemic someday, and nobody can predict when. In a commentary in the May 9, 2007 issue of the Journal of the American Medical Association, scientists at the National Institutes of Health discuss why predicting the next pandemic is so difficult and outline steps that can be taken to better understand the behavior of the virus.

HIV :: Marital sex single greatest HIV risk for women around the world

For a growing number of women in rural Mexico ? and around the world ? marital sex represents their single greatest risk for HIV infection. According to a new Mailman School of Public Health Study, because marital infidelity by men is so deeply ingrained across many cultures, existing HIV prevention programs are putting a growing number of women at risk of developing the HIV virus.

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