HIV :: A hairpin to fight HIV

When a host cell is infected with HIV, the virus brings its own genetic material into the host cell. This cell then replicates, reads the viral RNA, and uses it as a blueprint to produce more viral proteins. Complete viruses are then released to attack the next cells.

Obesity :: Possible link between obesity and viral infections

Experts don’t dispute the important role that diet and activity play in maintaining a healthy weight. But can poor eating habits and a less active lifestyle fully explain the prevalence of obesity in the United States today? That question has led some researchers to ask whether there might be other causes for this serious problem. In the October issue of Mayo Clinic Proceedings, researcher Richard Atkinson, M.D., asserts that there is a growing body of evidence demonstrating that viruses may play a role in causing obesity in humans.

Hepatitis C :: 24-week course of interferon-alpha therapy prolongs survival in patients hepatitis C virus

Patients with the hepatitis C virus (HCV) have a risk of frequent recurrence and deterioration of liver function, even after curative treatment for the primary hepatocellular carcinoma (HCC). This unfavorable prognosis is associated with a sustained HCV infection. Thus, both the prevention of HCC recurrence and the preservation of liver function are high priorities when trying to improve the prognosis of patients with HCV-related HCC. Antiviral therapy for chronic hepatitis C (HCV) after treatment for primary HCC is the essential factor required for an improved prognosis.

Anal Fissure :: A case of anal fissure – prescribing on the seat not the site

An anal fissure is a cut or tear occurring in the anus (the opening through which stool passes out of the body) that extends upwards into the anal canal. Patients may try to avoid defecation because of the pain. The pain may also affect urination causing dysuria, frequent urination, or the inability to urinate. Bleeding in small amounts, itching (pruritus ani), and a malodorous discharge may occur due to the discharge of pus from the fissure.

Bird Flu :: Need for preparedness for potential flu pandemic

Warning that the H5N1 virus responsible for bird flu could still transform itself into the next human influenza pandemic, a senior United Nations specialist has stressed the need to ensure that the world can respond promptly and effectively in the case of an outbreak.

Genome :: Consortium Publishes Phase II Map of Human Genetic Variation

The International HapMap Consortium today published analyses of its second-generation map of human genetic variation, which contains three times more markers than the initial version unveiled in 2005. In two papers in the journal Nature, the consortium describes how the higher resolution map offers greater power to detect genetic variants involved in common diseases, explore the structure of human genetic variation and learn how environmental factors, such as infectious agents, have shaped the human genome.

Flu :: No Vacation for Flu Virus

It’s almost flu season, so keep washing your hands and get a flu shot. But no matter how well we prepare, the virus stays one step ahead. Researchers now think that’s because the flu virus doesn’t vacation—it remains on duty throughout the year, traveling the globe and mixing with other strains.

HIV :: FDA approves new HIV drug raltegravir tablets

The U.S. Food and Drug Administration (FDA) has approved raltegravir tablets for treatment of Human Immunodeficiency Virus (HIV)-1 infection in combination with other antiretroviral agents in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

Cough :: Recommendations for the appropriate use of cough and cold products in children

Concerns have been raised regarding the safety of “over-the-counter” (non-prescription) cough and cold products in children. Health Canada is advising consumers on the appropriate use of these products, including drugs and natural health products, particularly in children under 2 years of age. Life-threatening adverse events, including unintentional overdose, have been reported to Health Canada in association with the use of these products in children under 2 years of age.

HIV :: FDA approves Merck’s Isentress, raltegravir tablets for HIV AIDS

Merck & Co., Inc., announced that the U.S. Food and Drug Administration (FDA) granted ISENTRESS TM (raltegravir) tablets accelerated approval for use in combination with other antiretroviral agents for the treatment of HIV-1 infection in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

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