Obesity :: Obesity dramatically increases kidney failure risk

Obesity has long been linked to heart disease, high blood pressure, and diabetes. Now, researchers are adding kidney failure to the list of ailments, as a new research has found that obese people have up to a seven times greater risk of developing end-stage renal disease, more simply known as kidney failure, than normal weight people.

Heart Disease :: Having a Sibling with Heart Disease

Having a sibling with a history of cardiovascular disease carries the same or greater risk as having a parent with a history of the disease, according to a new report from the long-standing Framingham Heart Study conducted by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health (NIH). Personal risk of having a cardiovascular event, such as a heart attack, stroke, or peripheral artery disease, may be raised by as much as 45 percent in middle-aged people whose brother or sister has had such an event.

Depression :: Identify Patients With Treatment-Resistant Depression

Initial results of the nation’s largest clinical trial for depression have helped clinicians to track ‘real world’ patients who became symptom-free and to identify those who were resistant to the initial treatment. Participants treated in both medical and specialty mental health care settings experienced a remission of symptoms in 12 to 14 weeks during well-monitored treatment with an antidepressant medication. The study, funded by the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH), used flexible adjustment of dosages based on quick and easy-to-use clinician ratings of symptoms and patient self-ratings of side effects.

Lupus :: Safety of Oral Contraceptives in Women with Lupus

In a major study funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body’s immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

Fertility :: Scientists discover fertility genes

Scientists at the Waksman Institute of Microbiology at Rutgers, The State University of New Jersey, have zeroed in on genes which are essential for fertilization . The proteins encoded by these genes are similar to low density lipoprotein (LDL) receptors, known from cholesterol and fat metabolism but never before specifically implicated in fertilization.

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