Bethesda, Md. ? The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health (NIH), today announced the latest round of grant awards totaling more than $13.3 million to speed the development of innovative sequencing technologies that reduce the cost of DNA sequencing and expand the use of genomics in medical research and health care.
Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) and other institutions have demonstrated for the first time that a single drug can rebuild damaged muscle in two strains of mice that develop diseases comparable to two human forms of muscular dystrophy. This advance, which is reported online in Nature Medicine, is the latest from a research collaboration that began several years ago by the teams of Vittorio Sartorelli, M.D., at NIAMS and Pier Lorenzo Puri, M.D., Ph.D., now at Dulbecco Telethon Institute (DTI) in Rome, Italy and The Burnham Institute in La Jolla, Calif.
About 1 in 100 babies delivered by caesarean section are injured in the process. The risk of injury is influenced by the reasons for doing the c-section.
Manhattan Pharmaceuticals, Inc. (Amex: MHA) today announced expansion of its oral Oleoyl-estrone (OE) clinical obesity program to include the morbidly obese. A new US Phase 2a clinical trial evaluating oral OE in morbidly obese male subjects will be initiated in October 2006. The morbidly obese population in the US is estimated to be 14 million people. OE is the Company’s orally administered product candidate in development for the treatment of obesity.
Eklin Medical Systems, Inc., a leader in digital radiography (DR), PACS (Picture Archiving and Communication System) and Practice Information Management software (PIMS) for the veterinary care market, announced the introduction of a comprehensive positioning guide for capturing diagnostic equine digital radiographs. The guide features Sheika, a petite gray Arabian mare, who was rescued by the founders of Peninsula Equine Medical Center before she was about to be euthanized by her owner. The 65-page guide provides a quick reference resource for veterinarians and technicians when imaging a horse’s feet, pasterns, fetlocks, stifles, skull, cervical spine and other pertinent anatomy.
Agile Therapeutics, a pharmaceutical development company focused on innovative transdermal products, is developing the next generation of contraceptive patches, one that is designed to deliver low doses of birth control hormones over a seven-day period.
The PATH Malaria Vaccine Initiative today announced the appointment of John G. McNeil, MD, MPH, as scientific director, effective immediately. Dr. McNeil will have principal responsibility for directing MVI’s early-stage vaccine development efforts and for shaping and managing MVI’s overall candidate vaccine portfolio.
A gene that makes cells in the eye receptive to light is missing in humans, researchers have discovered. They say that whereas some animals like birds, fish and amphibians have two versions of this photoreceptor, mammals, including humans, only have one. The findings – published in the Public Library of Science journal PLoS Biology – reveal how our experience of the light environment may be impoverished compared to other vertebrates and fits with the suggestion that early mammals were at one time wholly nocturnal creatures.
Researchers at The University of Manchester have been awarded 130,000 pounds to develop new techniques to reduce the need for animals in drug testing. Current checks to establish whether a new drug is carcinogenic can be inconclusive and require further testing on live animals to establish whether they are harmful or not.
IED is defined as repeated and uncontrollable anger attacks that often become violent. IED is different from common type of anger most people exhibit from time to time when they pout, throw a book down or walk out of the room banging door, activities that are better described as mild temper tantrums.