Antioxidant :: Antioxidants could provide all-purpose radiation protection

Two common dietary molecules found in legumes and bran could protect DNA from the harmful effects of radiation, researchers from the University of Maryland report. Inositol and inositol hexaphosphate (IP6) protected both human skin cells and a skin cancer-prone mouse from exposure to ultraviolet B (UVB) radiation, the damaging radiation found in sunlight, the team reported today at the American Association for Cancer Research Centennial Conference on Translational Cancer Medicine.

Lung Cancer :: Study identifies novel gene alterations in lung cancer

An international team of scientists, supported in part by the National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), announced that its systematic effort to map the genomic changes underlying lung cancer has uncovered a critical gene alteration not previously linked to any form of cancer. The research, published in the advance online issue of the journal Nature, also revealed more than 50 genomic regions that are frequently gained or lost in lung adenocarcinoma, the most common type of lung cancer in the United States.

HIV :: A hairpin to fight HIV

When a host cell is infected with HIV, the virus brings its own genetic material into the host cell. This cell then replicates, reads the viral RNA, and uses it as a blueprint to produce more viral proteins. Complete viruses are then released to attack the next cells.

HIV :: Testing delays cause severe AIDS complications, Einstein researchers find

Despite the availability of life-saving antiretroviral treatment, people infected with HIV (human immunodeficiency virus) continue to die and suffer from complications of AIDS, mainly due to delayed diagnosis and initiation of treatment. A researcher at the Albert Einstein College of Medicine of Yeshiva University and colleagues at Yale University have shed light on why this problem persists. They report their findings in the November issue of the journal Medical Care.

Liver :: Plasma serotonin levels can correlate with degree of liver insufficiency

Liver cirrhosis is a worldwide disease with an incidence of 5 – 10% and represents a major health problem everywhere. Prognosis depends on the degree of liver damage and etiology of cirrhosis. Treatment is complex and often very expensive. Due to this, the attempts of researchers are focused on finding the most optimal therapeutic modalities, which depend mostly on the stage of cirrhosis.

Pancreatitis :: Large dose dexamethasone plays important roles in severe acute pancreatitis

Severe acute pancreatitis (SAP) is a fatal systemic disease featuring acute onset, serious conditions, high incidence of complications and 20 – 30% mortality, mainly due to multiple organ failure at its early stage. The pathogenesis of SAP is closely related to factors such as activation of pancreatin, release of inflammatory mediators, microcirculation disturbance and apoptosis.

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