Cancer :: Improving care for cancer patients – Kerr, UK

One in five cancer patients in Scotland is still having to wait for treatment longer than the Executive?s own two-month target. But yesterday, health minister Andy Kerr promised improvements and revealed new ways for health boards to meet targets.

Breast Cancer :: Aeterna Zentaris – Positive Top Line Phase 1 Results for AN-152 in Gynaecological and Breast Cancers

?terna Zentaris Inc. (TSX: AEZ; NASDAQ: AEZS) today disclosed additional positive top line Phase 1 results for its cytotoxic conjugate AN-152 in patients with gynaecological and breast cancers. Further data showed the compound?s good safety profile and established the maximum tolerated dose (MTD) at 267 mg/m? which will be the recommended dose for a Phase 2 trial. In addition to good safety data, the trial provided a hint of efficacy as disease stabilization and regression of lesions were observed at the 160 mg/m? and 267 mg/m? dose levels.

Disinfectant :: Solvay’s Perestane effective against Clostridium difficile and MRSA

Perestane?, an innovative biocidal product created and developed by Solvay, has been proven to be an effective disinfectant against Methicillin-resistant Staphylococcus aureus (MRSA) and Clostridium difficile. These so-called ?superbugs? may cause fatal diseases, and the treatment of patients with most current antibiotics is ineffective. Researchers from the University of Leeds and Leeds General Infirmary (United Kingdom) have recently demonstrated that disinfectants commonly used in hospitals fail to eradicate Clostridium difficile from the premises, and may even promote spore formation.

Embolism :: Oral anticoagulant rivaroxaban shows efficacy and safety for prevention of VTE

Phase II clinical trial results published today in Circulation (2006;114:2374-2381) highlight the potential of a simple, once-daily dosing regimen of the novel, oral anticoagulant rivaroxaban (BAY 59-7939), a direct Factor Xa inhibitor. In this trial, rivaroxaban demonstrated that it may have similar safety and efficacy to subcutaneous enoxaparin (the current standard), for the prevention of venous thromboembolism (VTE) in patients undergoing elective total hip replacement surgery.

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