Treatment | Page 324 of 465

Transplant :: Preventing graft-versus-host disease after bone marrow transplant

Most patients undergoing bone-marrow transplant must receive powerful chemotherapy drugs to suppress their immune system and prevent their bodies from rejecting the donated cells. New research shows that this chemotherapy increases the risk for graft-versus-host disease — but also suggests that this risk can be reduced by replacing a natural antibiotic that’s depleted when patients undergo chemotherapy. A multicenter study led by Children’s Hospital Boston and the Dana-Farber Cancer Institute is about to test this idea.

Lung Cancer :: Successful lung cancer surgery not enough to break nicotine dependence in many smokers

A new study has found that close to half of 154 smokers who had surgery to remove early stage lung cancer picked up a cigarette again within 12 months of their potentially curative operation, and more than one-third were smoking at the one year mark. Sixty percent of patients who started smoking again did so within two months of surgery.

Tumor :: Report calls for improved monoclonal antibodies against solid tumors

A new report by leading experts in monoclonal antibody research for oncology offers a conceptual framework for future research in the design of antibody therapies against solid tumors.

Leukemia :: New tools to fight leukemia – chronic lymphocytic leukemia CLL

Mayo Clinic Cancer Center, working in collaboration with Ohio State University Comprehensive Cancer Center, presented evidence Sunday that a novel regimen of three chemotherapy drugs, pentostatin, cyclophosphamide and rituximab, resulted in significant clinical response in patients with previously untreated chronic lymphocytic leukemia (CLL).

Cancer :: Cancer immunoresistance linked to loss of tumor suppressor gene

Cancer immunoresistance may be partially due to loss of a well-known tumor suppressor gene, according to new research led by Andrew T. Parsa, MD, PhD, assistant professor of neurological surgery at the University of California, San Francisco.

DNA :: Evolution and the workaround

At the American Society for Cell Biology 2006 conference, scientists will describe new research indicating that both yeast and cancer cells evolve chromosome duplications to work around lethal stresses.

Pneumonia :: Early use of oral antibiotics in severe community acquired pneumonia

Switching intravenous antibiotics to the oral route after three days in patients with severe community acquired pneumonia shortens hospital stay and seems to be safe.

Diabetes :: How to achieve strict glycaemic control in type 2 diabetes

Effective treatment of hyperglycaemia and strict glycaemic control are key to reducing microvascular complications in patients with type 2 diabetes.

Dementia :: Occupational therapy for dementia improves function

Community based occupational therapy for elderly patients with dementia improves daily function and reduces the burden on carers say Graff and colleagues.

Multiple Myeloma :: Individualizing treatment for multiple myeloma patients

Researchers at Mayo Clinic Cancer Center, in cooperation with industry partners, have, for the first time, identified tumor specific alterations in the cellular pathway by which the multiple myeloma drug bortezomib (Velcade) works, and they have identified nine new genetic mutations in cancer cells that should increase a patient’s chance of responding to the agent.