Imminent arrival of latest HIV drug darunavir, when combined with FUZEON, will give treatment-experienced patients a better chance to achieve undetectable viral load.
Johns Hopkins scientists have discovered that women treated for ovarian cancer are at increased risk of a rapid and potentially fatal recurrence if their tumor cells have high levels of a binding protein that triggers abnormal growth and slows down cell death, both hallmarks of malignancy.
The U. S. Food and Drug Administration (FDA) today approved the first generic version of Wellbutrin XL (Bupropion hydrochloride) Extended-Release Tablets, which are indicated for the treatment of major depressive disorder (MDD). The approval is an important step in the agency’s effort to increase the availability of lower-cost generic medications. In 2005, Wellbutrin XL was the 21st highest-selling brand-name drug in the United States, with sales totaling $1,326,323,000 as reported in the online magazine Drug Topics.
A drug commonly used to slow the loss of central vision has shown promise in stemming a common precursor of blindness in diabetics, which involves the same central light-sensitive area of retina, Johns Hopkins Wilmer Eye Institute scientists report.
New data from the National Surgical Adjuvant Breast and Bowel Project (NSABP) B-33 study, presented today at the San Antonio Breast Cancer Symposium, showed that postmenopausal women with hormone receptor-positive breast cancer who received Aromasin after five years of tamoxifen were 56 percent less likely to have a relapse of breast cancer than those who received placebo.
Expression of two different proteins taken from primary tumor biopsies is highly associated with spread of breast cancer to nearby lymph nodes, according to researchers who say this protein profile could help identify at an early stage those patients whose disease is likely to metastasize.
Researchers at Ohio State University have discovered that two microRNA (miRNA) molecules help control the oncogene responsible for a dangerous form of B-cell chronic lymphocytic leukemia (B-CLL), the most common human leukemia in the world.
Scientists have discovered that induction of a gene known as MDA-7/IL-24 is the molecular mechanism that enables nonsteroidal anti-inflammatory drugs (NSAIDs) to halt the growth of cancer cells, a finding that could eventually lead to the development of targeted cancer treatments.
Scientists at the Scripps Research Institute, the University of Wisconsin School of Medicine and Public Health, and the Howard Hughes Medical Institute have revealed in atomic detail how the toxins that cause botulism target and bind to nerve cells. This new understanding could ultimately lead to new ways for treating botulism, as well as to improved therapies for nervous system diseases such as dystonias, cerebral palsy and multiple sclerosis.
The International AIDS Vaccine Initiative (IAVI) issued this statement today following a National Institutes of Health (NIH) decision to end two clinical trials of adult male circumcision in Uganda and Kenya. The NIH’s Data Safety and Monitoring Board (DSMB), reviewing interim data, found that medically performed circumcision significantly protected men in the trial from HIV infection.