Cancer researchers have long worked to understand why some prostate cancers recur after the use of therapies designed to stop the production of testosterone and other androgens that fuel cancer cell growth. New research has now detected that androgen-synthesizing proteins are present within cancer cells, which suggests that cancer cells may develop the capacity to produce their own androgens.
Based on POSSUM, a system suggested by some British scholars more than 10 years ago, a team led by Dr. Lian-An Ding has established the M-POSSUM evaluation system with the aim of improving the accuracy and effectiveness of the original system.
An intravenous “blood thinner” widely used in patients with acute coronary syndromes and during coronary artery stent placement appears to be safe in patients with sickle cell disease and may have beneficial anti-inflammatory effects, a small study at the University of North Carolina at Chapel Hill School of Medicine has found.
A research team led by Dr. Paul Harch, Assistant Professor of Clinical Medicine at Louisiana State University Health Sciences Center New Orleans and Director of the LSU Hyperbaric Medicine Fellowship Program, has published findings that show hyperbaric oxygen therapy improved spatial learning and memory in a model of chronic traumatic brain injury.
Researchers have discovered new small molecules that may prevent prostate cancer cells from turning off normal genes in a process that transforms normal cells into cancer cells. This significant discovery in the field of epigenetics has immediate implications in the development of new diagnostic tests and cancer medications.
Through the generous philanthropic support of the Littlefield 2000 Trust, the American Association for Cancer Research is pleased to announce four recipients of the 2007 Jeannik M. Littlefield-AACR Grants for Metastatic Colon Cancer Research, totaling $2.7 million. Now in its second year, this competitive grant program supports the cutting-edge research of top scientists from around the world, working to accelerate the discovery and development of new treatments for metastatic colon cancer.
Women who overcome breast cancer have every reason to celebrate. But a heart filled with joy may also be a heart damaged by life-saving cancer therapies, a growing body of research shows.
Grantees of the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, have adapted a rapid and accurate new molecular typing strategy and used it to conduct one of the most comprehensive studies of adenoviruses ever performed in the United States.
Men who have prostate cancer are on average four times more likely to suffer a hip fracture, with rates rising to eight times in men aged 50 to 65, according to a study of more than 60,000 men published in the October issue of the urology journal BJU International. Danish researchers looked at 62,865 men aged 50 and over, with an average age of just under 67.
In rats with portal hypertension, ultra¨Clow-dose aspirin has shown a normalizing effect of platelet-endothelial cell alterations and bleeding time. Further, this effect is mediated by Cyclooxygenase 2 inhibition.