Bioengineers have painstakingly assembled a first-of-its-kind virtual human metabolic network that offers a new way to hunt for better treatments for hundreds of human metabolic disorders, from diabetes to high levels of cholesterol in the blood.
A new technique employs RNA to turn on genes could lead to therapeutics for conditions in which nudging a gene awake would help alleviate disease, researchers at UT Southwestern Medical Center say.
For decades, a debate has simmered in the educational community over the best way to teach children how to read.
There is near-universal agreement about the need for clinical researchers to disclose financial interests to research participants, but until now there has been little guidance available on exactly how to do it. Using an empirically-based approach, team creates new tool to do the right thing.
GAIKER-IK4 Technological Centre’s Area of Biotechnology, together with the Opthtalmological Surgery Clinical Institute of Bilbao (ICQO) are co-operating in a research project the aim of which is to develop a diagnostic system, based on immunochromatographic techniques, for the specific recognition of proteic markers for ocular pathologies in eye teardrop samples.
Dana-Farber Cancer Institute researchers have developed a powerful method for charting the positions of key gene-regulating molecules called nucleosomes throughout the human genome. The mapping tool could help uncover important clues for understanding and diagnosing cancer and other diseases, the scientists say. Moreover, it may shed light on the role of nucleosomes in the process of “reprogramming” an adult cell to its original embryonic state, which is a critical operation in cloning.
A gene that apparently can raise the risk of developing the most common form of dementia – Alzheimer’s disease, has been identified and this may help scientists develop new treatments for Alzheimer’s Disease.
Scientists from the Institute for Research in Biomedicine (IRB Barcelona), the Life Sciences Program at the Barcelona Supercomputing Center (BSC) and the National Institute for Bioinformatics (INB) have published a provisional “atlas” of the dynamic behaviour of proteins in the prestigious scientific journal, Proceedings of the National Academy of Sciences.
Thai researchers have discovered that patients who fail treatment with a commonly used, inexpensive, first-line antiretroviral therapy (ART) are also usually resistant to other, similar drugs, leaving progressively fewer options for replacement therapies. Since catching treatment failure early is key to preventing further resistance, this research, published in the February 1 issue of Clinical Infectious Diseases also argues for greater access in the developing world to tests that detect when the amount of virus in a patient’s blood is increasing.
Nurses with higher levels of hopefulness are more likely to report feeling confident and competent in their ability to care for dying children and their families. Based on a survey of hundreds of pediatric nurses, researchers found that nurses who were more confident about their skills also were more likely to have received education in palliative care — the practice of providing high-quality, responsive care to patients with a life-threatening illness.