An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva.
Researchers from MetroHealth Medical Center and Case Western Reserve University in Cleveland, OH found that treating expectant mothers who have had previous spontaneous preterm births with 17 Alpha Hydroxyprogesterone caproate (17P) and reducing the incidence of another preterm birth would consequently reduce both short-term and lifetime medical costs in offspring by $2 billion per year.
Garcia, et al reported their experience with renal transplantation in 38 children (40 transplant), ages 1-5 years over a 16 year period. Demographics as well as patient and graft survivals were all reported. The mean age at transplantation was 3.3 ? 1.3 years and the mean weight was 14 kilograms with a range of 5.7-25 kg. The population consisted of 92.5% Caucasian, 7.5% African Brazilian. The main etiology for end-stage renal disease was uropathic/vesicoureteral reflux in 45% of the children followed by glomerulopathy in 25%, congenital/hereditary disease in 10% and hemolytic uremic syndrome at 12.5%. Prior to transplantation, 5% were on hemodialysis, 85% on peritoneal dialysis, and 10% were preemptive transplants.
INTERMACS, the Interagency Registry for Mechanically Assisted Circulatory Support, and its role in facilitating ongoing development of ventricular assistive devices (VAD) will be the subject of presentations and discussion during the International Society for Heart and Lung Transplantation (ISHLT) 27th Annual Meeting and Scientific Sessions this week.
Wan, et al evaluated 95 infants who presented with a urinary tract infection. They reviewed the clinical and laboratory findings as well as the diagnosis and treatment.
The anti-anginal medication ranolazine was shown to be safe in regard to certain outcomes but did not reduce the risk of major cardiovascular events such as death, heart attack or recurrent ischemia following acute coronary syndromes, according to a study in the April 25 issue of JAMA.
Many women in the menopausal transition experience hot flashes: unpredictable, sometimes disruptive, periods of intense heat in the upper torso, neck and face. Although generations of physicians have prescribed hormones to reduce these symptoms, very little research has focused on the underlying causes of hot flashes.
Some say age 90 is the new age 70. If so, there’s never been a better time for elderly patients to discuss with family and physicians just how aggressive medical care should be in case of a threatened or definite heart attack.
Researchers at the Ireland Cancer Center of University Hospitals Case Medical Center have developed methods for treating lung cancer cells that have become resistant to new anti-cancer agents.
Many patients diagnosed with HIV in the 1980s and 1990s have survived and now are entering their golden years. AIDS cases among the over-50 crowd reached 90,000 in 2003, and according to the Centers for Disease Control and Prevention, will account for half of all HIV/AIDS cases in the United States by 2015.