The American College of Cardiology and the American Heart Association have jointly released revised Guidelines for the Management of Patients with Unstable Angina (UA)/Non-ST- Elevation Myocardial Infarction (NSTEMI).
A potential new biomarker for heart failure may be more powerful than established measures in identifying patients at increased risk for death from several causes. In a report to appear in the Journal of the American College of Cardiology that has received early online release, an international research team describes finding that blood levels of a protein called ST2 both indicate the presence of heart failure among patient with shortness of breath and powerfully predict the risk that a patient will die during the following year.
People suffering from a severe retinal disease will sooner or later lose their eyesight considerably or even become completely blind. Those affected, family members, researchers and doctors hope that this fate might be avoided one day by a better understanding of the reasons for this disease.
Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.
A report from researchers at Children’s Hospital Boston and the Harvard Stem Cell Institute sheds new light on a now-discredited Korean embryonic stem cell line, setting the historical record straight and also establishing a much-needed set of standards for characterizing human embryonic stem cells. The report was published online August 2 by the journal Cell Stem Cell.
Cancer causing mutations occur in our bodies every day ? but luckily, we have specific genes that recognize these malignant events and keep cells from growing out of control. Only a few of these genes ? called tumor suppressors ? are currently known.
Artificially inducing menopause may reduce breast cancer recurrence in premenopausal women with early-stage breast cancers.
Massachusetts General Hospital (MGH) researchers have identified a key mechanism underlying proteinuria – excess protein in the urine which signifies a breakdown in the kidney’s filtering process. They have discovered that a protein called dynamin is required for the function of a critical filtering structure called a podocyte and that a specific enzyme’s processing of dynamin will cause podocytes to break down, allowing protein to leak out of the bloodstream.
New Mental Health Minister Ivan Lewis in his first major announcement, signalled the Government’s commitment to lead a radical change in the way mental health services are delivered. He today gave the go-ahead for eleven new projects which will allow people with anxiety and depression better access to psychological therapies.
In an effort to find a better therapy and improve the lives of people with epilepsy, the Massachusetts General Hospital (MGH) Epilepsy Service is participating in the RNS? System Pivotal Clinical Investigation, a study to evaluate the safety and effectiveness of a responsive brain stimulation device in reducing the frequency of uncontrolled seizures. MGH is one of only 28 centers across the country participating in this study.