Leukemia :: Arranon for Rare Leukemia and Lymphoma

The Food and Drug Administration (FDA) announced the approval of Arranon (nelarabine) for marketing in the United States. This is a new drug to treat adults and children with T-cell acute lymphoblastic leukemia (T-ALL) and T-cell lymphoblastic lymphoma (T-LBL), whose disease has not responded to or has relapsed following at least two chemotherapy regimens. Arranon is the first drug to treat this limited population of patients.

Obesity :: Weight loss lowers hormone levels in obese kids

A condition involving abnormally high levels of androgens (steroid hormones) known in medical circles as “hyperandrogenemia” starts early in obese children, a study shows, possibly placing them at increased risk for the metabolic syndrome — a cluster of conditions such as high blood pressure and high blood sugar levels that raise the risk of heart disease and diabetes.

Heart Disease :: Cost-effective implantable cardioverter defibrillators

The use of implanted defibrillators that keep the heart beating in proper electrical rhythm to prevent cardiac arrest appears to be cost-effective for those patients who receive a significant mortality reduction, according to researchers from Duke Clinical Research Institute (DCRI), Stanford University and the VA Palo Alto Health Care System, Calif.

Hidradenitis :: Treatment of hidradenitis suppurativa

Hidradenitis suppurativa is primarily a disease of occlusion (obstruction) and inflammation of the apocrine (odor) sweat glands of the groin and axilla (armpit). It is similar to acne, which is a disease of the sebaceous (oil) glands in the skin. Hidradenitis develops when ducts from the apocrine glands to the skin surface become blocked, leading to a red swollen area on the skin and to the formation of cysts, infection and scarring.

Menopause :: Alternative therapies for managing menopausal symptoms

Deciding whether to use hormone therapy (HT) after menopause is a difficult decision many women face as they age. Research has shown that HT is very effective for relieving menopausal symptoms such as hot flashes and vaginal dryness. It can also reduce the risk of osteoporosis. However, there are also known health risks and uncertainties about long-term use. Recent research has demonstrated that long-term use of estrogen–either alone or in combination with progestin–results in more risks than benefits.

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