Pancreatic Cancer :: Cytokeratin 20 Expression Linked to Poor Survival

According to an early on-line article published in the journal Cancer, strong expression of the protein cytokeratin 20 in pancreatic cancer is associated with significantly worse survival than low levels or no expression of cytokeratin 20. Patients diagnosed with pancreatic cancer who have a strong cytokeratin 20 expression may wish to undergo more aggressive therapy or participate in a clinical trial to improve their outcomes.

Leukemia :: Older AML patients do not benefit from more therapy

According to results presented at the 47th annual meeting of the American Society of Hematology (ASH), patients 60 years of age and over diagnosed with acute myeloid leukemia (AML) do not benefit from increased doses of the commonly used chemotherapy agents daunorubicin (Cerubidine?) or cytarabine (Cytosar-U?); as well, increasing the number of treatment courses of subsequent chemotherapy does not provide benefit.

Back Pain :: Surgical Options For Back Pain Sufferers

According to the American Association of Neurological Surgeons (AANS) between 75 and 85 percent of all Americans will suffer from low back pain at some point in their lives. However lumbar fusion is proving to be highly effective for the 10 percent of patients who require surgery.

Depression :: Identify Patients With Treatment-Resistant Depression

Initial results of the nation’s largest clinical trial for depression have helped clinicians to track ‘real world’ patients who became symptom-free and to identify those who were resistant to the initial treatment. Participants treated in both medical and specialty mental health care settings experienced a remission of symptoms in 12 to 14 weeks during well-monitored treatment with an antidepressant medication. The study, funded by the National Institutes of Health’s (NIH) National Institute of Mental Health (NIMH), used flexible adjustment of dosages based on quick and easy-to-use clinician ratings of symptoms and patient self-ratings of side effects.

Lupus :: Safety of Oral Contraceptives in Women with Lupus

In a major study funded by the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), a part of the National Institutes of Health (NIH), women with either inactive or stable systemic lupus erythematosus (lupus) – a disease in which the body’s immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs – were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that characterize the disease.

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