Gene therapy for hereditary lung disease advances

A clinical trial to evaluate the safety of using a so-called gene vector to deliver a corrective gene to 12 patients with a common hereditary disorder that causes lung and liver disease is completed at the University of Florida. The gene therapy has caused no harmful effects in patients and hints at being effective.

COPD :: Home Oxygen Therapy for COPD – Clinical Trial

The National Heart, Lung, and Blood Institute (NHLBI), one of the National Institutes of Health (NIH), and the Centers for Medicare & Medicaid Services (CMS) is launching the largest randomized clinical trial of the effectiveness and safety of long-term, home oxygen therapy for COPD (chronic obstructive pulmonary disease). The six-year, $28 million project will study patients with moderate disease.

HIV :: 24-week results from Aptivus, tipranavir

Data from two 24-week analyses of the RESIST-1 and RESIST-2 studies, which evaluated Aptivus? (tipranavir) in treatment-experienced HIV-1 infected patients, were published in the 15 November issue of Clinical Infectious Diseases. Data demonstrate that at 24-weeks Aptivus, used with ritonavir (Aptivus/r) as part of combination antiretroviral therapy, achieved superior antiviral and immunological activity in treatment-experienced patients with multidrug-resistant HIV-1 infection.

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