Prostate Cancer :: Aging gene also protects against prostate cancer development

Cancer researchers have found that a gene that is involved in regulating aging also blocks prostate cancer cell growth. They have shown that the enzyme SIRT1 can block the growth of treatment-resistant prostate cancer cells that overexpress a mutation for the androgen receptor. The scientists hope the newly found connection will aid in better understanding the development of prostate cancer and lead to new drugs against the disease.

Breast Cancer :: Quest for better breast cancer drugs

Breast cancer sufferers could eventually benefit from high-tuned, tailor-made drug treatments that minimize side effects as a result of a joint initiative between computer scientists in Edinburgh and cellular biologists in Japan.

Prostate :: Octogenarians are not too old for cancer surgery

Mayo Clinic Cancer Center researchers have found that a radical prostatectomy can be a viable option for select octogenarian patients. The findings, which run counter the conventional practice of generally avoiding surgeries for individuals over 80 years old solely based on age, are available today in Urology.

HIV :: Human testis harbors HIV-1 in resident immune cells

Researchers have demonstrated HIV replication within resident immune cells of the testis, providing an explanation for the persistence of virus in semen even after effective highly active antiretroviral therapy. The related report by Roulet et al., “Susceptibility of human testis to human immunodeficiency virus-1 infection in situ and in vitro,” appears in the December issue of the American Journal of Pathology.

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