Gene :: UVa researchers restore genes in human inner ear cells

Researchers at the University of Virginia Health System have discovered a way to transfer genes, which they hope will restore hearing, into diseased tissue of the human inner ear. This important step brings scientists closer to curing genetic or acquired hearing loss. Their discovery will appear Thursday, June 14, in the online issue of the scientific journal, Gene Therapy.

RNA :: Scientists decode RNA mystery, will help aim drug therapies

As reported in the June 13 issue of the online journal PLoS ONE, researchers led by Jonathan Dinman, assistant professor of cell biology and molecular genetics at the University of Maryland, have found the difference between two closely related components in the messenger RNA — near-cognate and non-cognate codons — terms that have long been used, but not understood.

Gene :: UVa-led team uncovers important secret in gene replication

A team of researchers led by University of Virginia Health System geneticists has uncovered a major secret in the mystery of how the DNA helix replicates itself time after time. It turns out that it is not just the sequence of the bases — building blocks — in the DNA, but also how loosely or tightly the chromatin — the material that makes up chromosomes — is packed at different points of the chromosome that is critical.

Genome :: The wider view from a detailed focus

A major study of the organization and regulation of the human genome published today changes our concept of how our genome works. The integrated study is an exhaustive analysis of 1% of the genome that, for the first time, gives an extensive view of genetic activity alongside the cellular machinery that allows DNA to be read and replicated.

Cancer :: Progress toward an antitumor vaccine

A team led by Horst Kunst at the University of Mainz has found a way to bind a molecule that is typical for tumors to a carrier protein without irritating the immune system. As they report in the journal Angewandte Chemie, their method is based on an immunocompatible connection by way of a sulfur atom, namely, a thioether.

Fitness :: To keep fit in space, train like an athlete

If one part of your car isn’t properly maintained, it can affect how the entire vehicle runs ? especially if you’re taking a long trip. The same can be said for the human body. That?s why, when it comes to fitness in space, it?s important to create a program addressing the whole system, parts included.

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