Surgery :: Advanced technology to revolutionize surgical care

A new Surgical Simulation and Technology Center at the University of Maryland Medical Center, one of only a few hospital-based centers of its kind in the United States, will open on December 6, 2006. The center brings together a diverse group of experts to solve important challenges in surgery, such as how to improve and expand minimally invasive surgical procedures that enhance patient care, how to advance the design of surgical instruments and how to redesign operating rooms to prevent surgeons from suffering from shoulder and neck injuries.

DNA :: Brown scientists map structure of DNA-doctoring protein complex

Mobile DNA, which inserts foreign genes into target cells, is a powerful force in the march of evolution and the spread of disease. Working with the lambda virus and E. coli bacteria, Brown University biologists have solved the structure of a six-protein complex critical to performing this gene-grafting surgery. The technique they developed could be used to reveal the structure of other critical protein complexes, landing the work on the cover of Molecular Cell.

Body Mass Index :: Blame our evolutionary risk of cancer on body mass

A key enzyme that cuts short our cellular lifespan in an effort to thwart cancer has now been linked to body mass.Until now, scientists believed that our relatively long lifespans controlled the expression of telomerase — an enzyme that can lengthen the lives of cells, but can also increase the rate of cancer.

Arthritis :: How movement lubricates bone joints

Researchers have shown that sliding forces applied to cartilage surfaces prompt cells in that tissue to produce molecules that lubricate and protect joints, an important step toward their goal of eventually growing joint tissue for transplantation.

Heartburn :: Better screening for people with chronic heartburn, precancer of the esophagus

Researchers in the Oregon Health & Science University Digestive Health Center are first to report that screening people with chronic heartburn or pre-cancer of the esophagus in an office setting using a “skinny scope” is as accurate, less expensive and less risky than a traditional sedated screening in a procedure room — and patients prefer it. The findings are published online and in print in this month’s issue of the American Journal of Gastroenterology.

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