Genome :: Genome update defines landscape of breast and colon cancers

One year after completing the first large-scale report sequencing breast and colon cancer genes, Johns Hopkins Kimmel Cancer Center scientists have studied the vast majority of protein-coding genes which now suggest a landscape dominated by genes that each are mutated in relatively few cancers.

Pancreatic Cancer :: Jefferson scientists find protein may be key in developing deadly form of pancreatic cancer

A tumor-blocking protein previously implicated in prostate and breast cancer development may also be behind the most aggressive type of pancreatic cancer. Researchers have discovered that the protein pp32 — which normally applies the brakes on a cancer-causing gene — is missing in an aggressive form of pancreatic cancer. Though the work is preliminary, the scientists say, the absent protein could eventually become a marker for the disease and a potential drug target.

Breast Cancer :: Breast reconstruction surgical webcast for breast cancer awareness month

Women with breast cancer often seek immediate breast reconstruction after a mastectomy to help them regain a semblance of their body and for their psychological peace of mind. As part of Breast Cancer Awareness Month in October, Thomas Jefferson University Hospital is re-airing its webcast on one of the most often performed breast reconstruction surgical procedures, using muscle tissue from a patient’s back.

Prostate Cancer :: Surgery may offer best chance of long-term prostate cancer survival

A study from Switzerland suggests that men who have surgery for prostate cancer appear less likely to die of the disease within 10 years than men who choose other treatment options, especially if they are younger or have cancers with certain tumor cell characteristics, according to a report in the Oct. 8 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.

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