Immune System :: How disease bacterium survives inside immune system cell

New research on a bacterium that can survive encounters with specific immune system cells has strengthened scientists? belief that these plentiful white blood cells, known as neutrophils, dictate whether our immune system will permit or prevent bacterial infections. A paper describing the research was released today online in The Journal of Immunology. Frank R. DeLeo, Ph.D., of Rocky Mountain Laboratories (RML), part of the National Institute of Allergy and Infectious Diseases (NIAID) of the National Institutes of Health, directed the work at RML, in Hamilton, MT, in collaboration with lead author Dori L. Borjesson, D.V.M., Ph.D., of the University of Minnesota in St. Paul.

Breast Cancer :: Bevacizumab and chemotherapy improve breast cancer

Preliminary results from a large, randomized clinical trial for patients with previously untreated recurrent or metastatic breast cancer – cancer that has spread from the breast to other parts of the body – show that those patients who received bevacizumab (Avastin) in combination with standard chemotherapy had a longer time period before their cancer progressed than patients who received the same chemotherapy without bevacizumab.

Oral cancer :: Success using saliva to detect oral cancer

Scientists funded by the National Institute of Dental and Craniofacial Research, part of the National Institutes of Health, reported today taking a major step forward in using saliva to detect oral cancer. As published in the current issue of Clinical Cancer Research, the scientists found they could measure for elevated levels of four distinct cancer-associated molecules in saliva and distinguish with 91 percent accuracy between healthy people and those diagnosed with oral squamous cell carcinoma.

Alzheimer’s disease :: Smelling test detects Alzheimer’s risk

People who have mild memory problems but who can correctly identify the source of certain smells are probably not in the first stages of Alzheimer’s disease, suggesting that smell tests could offer a new technique for early diagnosis, researchers reported.

HIV :: Two Cipla AIDS medicines back on WHO prequalification list

The World Health Organization (WHO) is reinstating two antiretrovirals manufactured by Cipla Ltd., India, in its list of prequalified medicines. The two medicines (which are used in the treatment of AIDS) had been delisted by WHO in May this year due to non-compliance with international standards at the contract research organizations (CROs) hired by Cipla to conduct bioequivalence tests on the products.

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