Breast Cancer :: Few early-stage breast cancer patients follow hormonal therapy plan

Postmenopausal women with early-stage, hormone-sensitive breast cancer have a lower risk of disease recurrence when their treatment includes a new class of hormone therapy drugs, yet one out five women prescribed the drugs may not take them regularly, according to a study conducted by researchers at Dana-Farber Cancer Institute and AstraZeneca Pharmaceuticals.

Circumcision :: Adult Male Circumcision Significantly Reduces Risk of Acquiring HIV

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), announced an early end to two clinical trials of adult male circumcision because an interim review of trial data revealed that medically performed circumcision significantly reduces a man’s risk of acquiring HIV through heterosexual intercourse.

Cancer :: How NSAIDs halt cancer growth explained

Scientists have discovered that induction of a gene known as MDA-7/IL-24 is the molecular mechanism that enables nonsteroidal anti-inflammatory drugs (NSAIDs) to halt the growth of cancer cells, a finding that could eventually lead to the development of targeted cancer treatments.

Brain :: Beyond the book – Software automates access to brain atlases

USC computer scientists have found a cheap, quick and copyright-respecting way to turn existing print brain atlases into multimedia resources. The software, now available in an experimental beta version for free download, is a robust and user-friendly interface that works on all the most popular computer operating systems.

Botulism :: Molecular basis of botulism toxin’s deadly activity

Scientists at the Scripps Research Institute, the University of Wisconsin School of Medicine and Public Health, and the Howard Hughes Medical Institute have revealed in atomic detail how the toxins that cause botulism target and bind to nerve cells. This new understanding could ultimately lead to new ways for treating botulism, as well as to improved therapies for nervous system diseases such as dystonias, cerebral palsy and multiple sclerosis.

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