Scientists have discovered new information about an immune pathway in mice that explains how oxidative stress that results from acute estrogen deficiency leads to the loss of bone. The finding, published in the Proceedings of the National Academy of Sciences, could help in identifying a new drug target for preventing postmenopausal bone loss.
Being moderately overweight or obese appears to increase the risk for developing coronary heart disease events independent of traditional cardiovascular risk factors, according to a meta-analysis of previously published studies in the September 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
Consuming higher levels of the yellow plant pigments lutein and zeaxanthin may be associated with a lower risk for age-related macular degeneration, according to a report in the September issue of Archives of Ophthalmology, one of the JAMA/Archives journals.
Mutations in the insulin gene can cause permanent neonatal diabetes, an unusual form of diabetes that affects very young children and results in lifelong dependence on insulin injections, report researchers from the University of Chicago and Peninsula University (Exeter, UK) in Sept. 18, 2007, issue of the Proceedings of the National Academy of Sciences, published early online.
GenVec, Inc. (Nasdaq: GNVC) announced that it has entered into a collaborative research and development agreement (CRADA) with the U.S. Military Malaria Vaccine Program at the Walter Reed Army Institute of Research (WRAIR) and the Naval Medical Research Center (NMRC) for the development and pre-clinical testing of a malaria vaccine candidate against Plasmodium vivax (P. vivax).
Scientists at Johns Hopkins have developed a mouse model for schizophrenia in which a mutated gene linked to schizophrenia can be turned on or off at will.
Researchers at the Johns Hopkins Malaria Research Institute (JHMRI) have identified a sugar in mosquitoes that allows the malaria-causing parasite, Plasmodium falciparum, to attach itself to the mosquito?s gut.
A Mediterranean diet may help people with Alzheimer?s disease live longer than patients who eat a more traditional Western diet. The study is published in the September 11, 2007, issue of Neurology?, the medical journal of the American Academy of Neurology.
Individuals who take vitamin D supplements appear to have a lower risk of death from any cause over an average follow-up time of six-years, according to a meta-analysis of 18 previously published studies in the September 10 issue of Archives of Internal Medicine, one of the JAMA/Archives journals.
A new study provides evidence that noncoding RNAs and interactions between noncoding genes play a much greater role in human cancer than was previously understood.