Schizophrenia :: How schizophrenia develops, major clues discovered

Schizophrenia may occur, in part, because of a problem in an intermittent on/off switch for a gene involved in making a key chemical messenger in the brain, scientists have found in a study of human brain tissue. The researchers found that the gene is turned on at increasingly high rates during normal development of the prefrontal cortex, the part of the brain involved in higher functions like thinking and decision-making — but that this normal increase may not occur in people with schizophrenia.

Drug :: Computational modeling could improve antibody drugs

Scientists have developed computational models that could improve the effectiveness of drugs based on antibodies. By calculating which molecular changes would cause the antibodies to bind more tightly to their targets, the models already have helped create a new version of an anticancer drug.

Garlic :: Garlic good for heart, relaxes arteries

Eating garlic is one of the best ways to lower high blood pressure and protect yourself from cardiovascular disease. A new study from the University of Alabama at Birmingham (UAB) shows this protective effect is closely linked to how much hydrogen sulfide (H2S) is produced from garlic compounds interacting with red blood cells.

HIV :: FDA approves new HIV drug raltegravir tablets

The U.S. Food and Drug Administration (FDA) has approved raltegravir tablets for treatment of Human Immunodeficiency Virus (HIV)-1 infection in combination with other antiretroviral agents in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

Acupuncture :: Acupuncture reduces pain, need for opioids after surgery

Using acupuncture before and during surgery significantly reduces the level of pain and the amount of potent painkillers needed by patients after the surgery is over, according to Duke University Medical Center anesthesiologists who combined data from 15 small randomized acupuncture clinical trials.

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