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Breast Cancer :: Enhanced DNA repair mechanism can cause breast cancer

Although defects in the “breast cancer gene,” BRCA1, have been known for years to increase the risk for breast cancer, exactly how it can lead to tumor growth has remained a mystery. In the October 15, 2007, issue of the journal Cancer Research, scientists from the University of Chicago and Kyoto University, Japan, suggest that a mechanism that normally repairs damaged DNA may function abnormally in BRCA1 carriers leading to one type of poor-prognosis breast cancer.

Obesity :: 1 in 5 bariatric surgery candidates not psychologically cleared for surgery

A new study by Rhode Island Hospital and Brown University researchers reported that 18 percent of 500 candidates for bariatric surgery did not receive the initial psychiatry clearance for the surgery. The study is the first to examine the reliability of decisions to clear candidates for surgery, and the largest to determine the percentage of candidates who are not cleared, and detail the reasons for exclusion.

Gene :: Genes that both extend life and protect against cancer identified

A person is 100 times more likely to get cancer at age 65 than at age 35. But new research reported today in the journal Nature Genetics identifies naturally occurring processes that allow many genes to both slow aging and protect against cancer in the much-studied C. elegans roundworm.

Smoking :: Cigarette smoking may accelerate disability in those with MS

Persons with multiple sclerosis who smoke risk increasing the amount of brain tissue shrinkage, a consequence of MS, and the subsequent severity of their disease, new research conducted at the Buffalo Neuroimaging Analysis Center (BNAC) at the University at Buffalo has shown.

HIV :: FDA approves Merck’s Isentress, raltegravir tablets for HIV AIDS

Merck & Co., Inc., announced that the U.S. Food and Drug Administration (FDA) granted ISENTRESS TM (raltegravir) tablets accelerated approval for use in combination with other antiretroviral agents for the treatment of HIV-1 infection in treatment-experienced adult patients who have evidence of viral replication and HIV-1 strains resistant to multiple antiretroviral agents.

Breast Cancer :: AACR, BCRF award inaugural grants in translational breast cancer research

Through the generous support of the Breast Cancer Research Foundation (BCRF), the American Association for Cancer Research (AACR) is pleased to announce the inaugural recipients of the 2007 BCRF-AACR Grants in Translational Breast Cancer Research. These grants provide direct support for innovative breast cancer research projects designed to accelerate the discovery, development, and application of new ways to treat breast cancer, or for preclinical research with direct therapeutic implications.

Parenting :: Study examines parent-child interactions in at-risk families

A closer look at the way parents interact with children may provide clues to mistreatment of kids and pave the way for potential interventions to prevent the problem.

Thrombosis :: Portal vein thrombosis is common in extraportal vein obstruction

Among the 118 patients with portal vein thrombosis, noncirrhotic and nontumoral extrahepatic portal vein obstruction are young and present with well tolerated bleed. Cirrhosis and tumor related portal vein thrombosis patients are older and have grim prognoses. Hypercoagulable state as a cause of portal vein thrombosis is less common. The idiopathic group comprises the second largest number of patients.

Foot and Mouth Disease :: Smiths Detection to launch a portable diagnostic system for foot-and-mouth disease and avian flu

Smiths Detection, part of the global technology business Smiths Group, today announces it is to launch a portable detection system that will enable veterinarians to carry out on-site diagnosis of animal diseases such as foot-and-mouth and avian flu. This new technology means vets will be able to diagnose diseases in livestock and birds in the field in less than 90 minutes rather than having to send samples for laboratory analysis.

Multiple Sclerosis :: MS that runs in families appears more severe than non-familial MS

Magnetic resonance images (MRI) of a large group of patients with multiple sclerosis has provided the first evidence that those with a history of MS in their families show more severe brain damage than patients who have no close relatives with the disease.